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Isoliquiritigenin

Isoliquiritigenin Structure
CAS No.
961-29-5
Chemical Name:
Isoliquiritigenin
Synonyms
ISL;ISOLIQUIRTIGENIN;(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one;gu17;Isoliquiritigen;Isqliquiritigenin;ISOLIQUIRITIGENIN;ISOLIQUIRITIGENIN(P);Isoliquiritigenin>Isoliquiritigenin-RM
CBNumber:
CB9131280
Molecular Formula:
C15H12O4
Molecular Weight:
256.25
MOL File:
961-29-5.mol
MSDS File:
SDS
Modify Date:
2024/11/17 8:48:38

Isoliquiritigenin Properties

Melting point 206-210°C
Boiling point 504.0±42.0 °C(Predicted)
Density 1.384±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: <0.1 mg/mL
pka 7.50±0.35(Predicted)
form powder
color yellow to orange
Sensitive Light Sensitive & Hygroscopic
BRN 1914296
InChIKey DXDRHHKMWQZJHT-FPYGCLRLSA-N
LogP 3.110 (est)
CAS DataBase Reference 961-29-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  36/37/38
Safety Statements  26-37
WGK Germany  3
RTECS  FL7080000
HS Code  29145090
NFPA 704
1
2 1

Isoliquiritigenin price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I3766 Isoliquiritigenin powder 961-29-5 10MG ₹43354.13 2022-06-14 Buy
Sigma-Aldrich(India) 38986 Isoliquiritigenin analytical standard 961-29-5 50MG ₹14949.33 2022-06-14 Buy
TCI Chemicals (India) I0822 Isoliquiritigenin 961-29-5 100MG ₹3200 2022-05-26 Buy
TCI Chemicals (India) I0822 Isoliquiritigenin 961-29-5 1G ₹5600 2022-05-26 Buy
Product number Packaging Price Buy
I3766 10MG ₹43354.13 Buy
38986 50MG ₹14949.33 Buy
I0822 100MG ₹3200 Buy
I0822 1G ₹5600 Buy

Isoliquiritigenin Chemical Properties,Uses,Production

Chemical Properties

Yellow solid

General Description

Isoliquiritigenin is an aromatic ketone and belongs to the chalcone group of compound. It is derived from licorice and is a component in medicine and food.

Anticancer Research

It is extracted from Dipteryx odorata seeds, found to be active in induction of quininereductase, and thus prevents chemical carcinogenesis. In a dose- and time-dependentmanner, it significantly inhibits the proliferation of prostate cancer cells,and this isoliquiritigenin-induced cell cycle arrest and antiproliferative effects maybe manifested by growth arrest- and DNA damage-inducible gene 153 (GADD153).It induces apoptosis in prostate cancer cells through mitochondrial apoptosispathway in which mitochondrial membrane potential is disrupted, cytochrome-cand Smac/Diablo are released, and caspase-9 is activated. It is reported to enhancethe expression of universal inhibitor of cyclin-dependent kinases, p21CIP1/WAF1, in adose- and time-dependent manner in A549 human lung cancer cells (Kanazawaet al. 2003; Ii et al. 2004; Balunas and Kinghorn 2005; Jung et al. 2006).

Isoliquiritigenin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 373)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6768 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12840 58 Inquiry
Hebei Chuanghai Biotechnology Co,.LTD +86-13131129325 China 5893 58 Inquiry
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD +86-15350851019 +86-15383190639 China 1000 58 Inquiry
Capot Chemical Co.,Ltd. +86-(0)57185586718 +86-13336195806 China 29791 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21634 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32951 60 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3772 58 Inquiry

Isoliquiritigenin Spectrum

gu17 Isqliquiritigenin ISOLIQUIRTEGENIN (2',4,4'-TRIHYDROXYCHAL ISOLIQUIRITIGENIN(P) ISOLIQUIRITIGENIN(RG) (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 4,2μ,4μ-Trihydroxychalcone Isoliquiritigenin,4,2',4'-Trihydroxychalcone (E)-2',4,4'-Trihydroxychalcone 2',4,4'-Trihydroxy-trans-chalcone 2’,4,4’-trihydroxy-chalcon 4,4’-trihydroxychalcone(e)-2 4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1-((e)-2-propen-1-on (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one 2',4,4'-Trihydroxychalcone Isoliquiritigenin, >=98% (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one Isoliquiritigenin (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one 2',4',4-TRIHYDROXYCHALCONE ISOLIQUIRITIGENIN (e)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one 4,2',4'-TRIHYDROXYCHALCONE Isoliquiritigenin 961-29-5 Isoliquiritigen Isoliquiritigenin> Isoliquiritigenin Standard 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)- Isoliquiritigenin USP/EP/BP Isoliquiritigenin (GU17) TIANFUCHEM--961-29-5--Isoliquiritigenin (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one ISL ISOLIQUIRTIGENIN Isoliquiritigenin Glycyrrhiza extract Isoliquiritigenin CAS Isoliquiritigenin-RM 961-29-5 BioChemical Cell Biology Cell Signaling and Neuroscience Cyclic Nucleotide Metabolism G Proteins and Cyclic Nucleotides Guanylyl Cyclase Activators The group of Liquorice sy Aromatics Intermediates & Fine Chemicals Pharmaceuticals Chalcones chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors