Isoliquiritigenin
- CAS No.
- 961-29-5
- Chemical Name:
- Isoliquiritigenin
- Synonyms
- ISL;ISOLIQUIRTIGENIN;(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one;gu17;Isoliquiritigen;Isqliquiritigenin;ISOLIQUIRITIGENIN;ISOLIQUIRITIGENIN(P);Isoliquiritigenin>Isoliquiritigenin-RM
- CBNumber:
- CB9131280
- Molecular Formula:
- C15H12O4
- Molecular Weight:
- 256.25
- MOL File:
- 961-29-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/17 8:48:38
Melting point | 206-210°C |
---|---|
Boiling point | 504.0±42.0 °C(Predicted) |
Density | 1.384±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | H2O: <0.1 mg/mL |
pka | 7.50±0.35(Predicted) |
form | powder |
color | yellow to orange |
Sensitive | Light Sensitive & Hygroscopic |
BRN | 1914296 |
InChIKey | DXDRHHKMWQZJHT-FPYGCLRLSA-N |
LogP | 3.110 (est) |
CAS DataBase Reference | 961-29-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-37 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | FL7080000 | |||||||||
HS Code | 29145090 | |||||||||
NFPA 704 |
|
Isoliquiritigenin price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | I3766 | Isoliquiritigenin powder | 961-29-5 | 10MG | ₹43354.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 38986 | Isoliquiritigenin analytical standard | 961-29-5 | 50MG | ₹14949.33 | 2022-06-14 | Buy |
TCI Chemicals (India) | I0822 | Isoliquiritigenin | 961-29-5 | 100MG | ₹3200 | 2022-05-26 | Buy |
TCI Chemicals (India) | I0822 | Isoliquiritigenin | 961-29-5 | 1G | ₹5600 | 2022-05-26 | Buy |
Isoliquiritigenin Chemical Properties,Uses,Production
Chemical Properties
Yellow solid
General Description
Isoliquiritigenin is an aromatic ketone and belongs to the chalcone group of compound. It is derived from licorice and is a component in medicine and food.
Anticancer Research
It is extracted from Dipteryx odorata seeds, found to be active in induction of quininereductase, and thus prevents chemical carcinogenesis. In a dose- and time-dependentmanner, it significantly inhibits the proliferation of prostate cancer cells,and this isoliquiritigenin-induced cell cycle arrest and antiproliferative effects maybe manifested by growth arrest- and DNA damage-inducible gene 153 (GADD153).It induces apoptosis in prostate cancer cells through mitochondrial apoptosispathway in which mitochondrial membrane potential is disrupted, cytochrome-cand Smac/Diablo are released, and caspase-9 is activated. It is reported to enhancethe expression of universal inhibitor of cyclin-dependent kinases, p21CIP1/WAF1, in adose- and time-dependent manner in A549 human lung cancer cells (Kanazawaet al. 2003; Ii et al. 2004; Balunas and Kinghorn 2005; Jung et al. 2006).
Isoliquiritigenin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12840 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | China | 5893 | 58 | Inquiry |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019 +86-15383190639 | China | 1000 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | China | 29791 | 60 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21634 | 55 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32951 | 60 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3772 | 58 | Inquiry |