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LOCHNERINE

LOCHNERINE Structure
CAS No.
522-47-4
Chemical Name:
LOCHNERINE
Synonyms
LOCHNERINE;Lochenerine;Luo Ke alkali;(+)-Lochnerine;(+)-Lochenerine;10-O-Methylsarpagine;10-Methoxynormacusine B;10-Methoxysarpagan-17-ol;Sarpagan-17-ol, 10-methoxy-;6,10-Methanoindolo[3,2-b]quinolizine-11-methanol,9-ethylidene-5,6,8,9,10,11,11a,12-octahydro-2-methoxy-,(6S,7R,9E,10R,11R,11aS)-
CBNumber:
CB51442961
Molecular Formula:
C20H24N2O2
Molecular Weight:
324.422
MOL File:
522-47-4.mol
MSDS File:
SDS
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LOCHNERINE Properties

Melting point 202.5-203.5°C

LOCHNERINE Chemical Properties,Uses,Production

Description

This carboline alkaloid has been obtained from Lochnera rosea and is also present in curare (Strychnos toxifera). Early preparations have been designated Alkaloid 'C' and C-Alkaloid T. It has [α]D + 56° (pyridine) or + n° (EtOH) and forms a crystalline picrate with a double melting point of 177-9°C and 243-5°C (dec.). The methiodide is identical with lochneram iodide, m.p. 235-8°C. A characteristic p-toluenesulphonyl derivative has been prepared, m.p. 153-4°C. One primary alcoholic hydroxyl is present and the alkaloid yields the O-acetate as colourless needles, m.p. 243°C; [α]D - 5.6° ± 3.0° (c 0.36, pyridine). The structure is that of O-methylsarpagine.

References

Janot, LeMen., Cornpt. rend., 243, 1789 (1956)
Mors et at., Chern. Ind., 173 (1956)
Arnold et at., Helv. Chirn. Acta, 40, 705 (1957)
Arnold et al., ibid, 41, 1505 (1958)
Karrer et at., Angew. Chern., 70,644 (1958)

LOCHNERINE Preparation Products And Raw materials

Raw materials

Preparation Products

LOCHNERINE Suppliers

Global( 54)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Xi'an Kono chem co., Ltd., 029-86107037 13289246953 China 2995 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
Shanghai Moqi Biological Technology Co., LTD 021-38218169 13341702378 China 9117 58 Inquiry
BioBioPha Co., Ltd. 0871-65217109 13211707573; China 5654 65 Inquiry
Shanghai Jizhi Biochemical Technology Co. Ltd. 400-400-400-9004166 18616739031 China 52712 58 Inquiry
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 China 7892 56 Inquiry
BioBioPha Co., Ltd. 0871-65217109 CHINA 6464 58 Inquiry
Supplier Advantage
Xi'an Kono chem co., Ltd., 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
Labnetwork lnc. 58
Alfa Chemistry 58
Shanghai Moqi Biological Technology Co., LTD 58
BioBioPha Co., Ltd. 65
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
BioBioPha Co., Ltd. 58

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LOCHNERINE (+)-Lochenerine 10-Methoxysarpagan-17-ol Lochenerine 10-Methoxynormacusine B 10-O-Methylsarpagine (+)-Lochnerine Sarpagan-17-ol, 10-methoxy- 6,10-Methanoindolo[3,2-b]quinolizine-11-methanol,9-ethylidene-5,6,8,9,10,11,11a,12-octahydro-2-methoxy-,(6S,7R,9E,10R,11R,11aS)- Luo Ke alkali 522-47-4