ChemicalBook > Product Catalog >API >Digestive system drugs >Other digestive system drugs >Castor oil

Castor oil

Castor oil Structure
CAS No.
8001-79-4
Chemical Name:
Castor oil
Synonyms
RICINUS COMMUNIS (CASTOR) SEED OIL;Castor;DEHYDRATED CASTOR OIL;Polyoxyl 35;neoloid;tor oil;Venelex;cosmetol;crystalo;goldbond
CBNumber:
CB5181661
Molecular Formula:
C57H104O9
Molecular Weight:
933.43026
MOL File:
8001-79-4.mol
Modify Date:
2024/5/18 8:51:57

Castor oil Properties

Melting point -10 °C
Boiling point 313 °C(lit.)
Density 0.955 g/mL at 25 °C
FEMA 2263 | CASTOR OIL (RICINUS COMMUNIS L.)
refractive index n20/D 1.478(lit.)
Flash point >230 °F
storage temp. Room Temperature, under inert atmosphere
solubility Miscible with chloroform, diethyl ether, ethanol, glacial acetic acid, and methanol; freely soluble in ethanol (95%) and petroleum ether; practically insoluble in water; practically insoluble in mineral oil unless mixed with another vegetable oil.
form Viscous Hygroscopic Liquid
color Clear almost colorless or slightly yellow
Specific Gravity 0.961
Odor Slight characteristic odor
optical activity [α]20/D +5°, c = 5 in ethanol
Water Solubility <0.1 g/100 mL at 20 ºC
FreezingPoint -10℃
Merck 14,1898
Dielectric constant 4.8(14℃)
Stability Stable. Combustible. Incompatible with strong oxidizing agents. May be light sensitive.
NIST Chemistry Reference Castor oil(8001-79-4)
EPA Substance Registry System Castor oil (8001-79-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Safety Statements  24/25
WGK Germany  -
RTECS  FI4100000
10
Autoignition Temperature 449°C
TSCA  Yes
HS Code  15153090
NFPA 704
1
1 0

Castor oil price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C9606 Castor oil meets testing specifications per USP 8001-79-4 500ML ₹22860 2022-06-14 Buy
Sigma-Aldrich(India) PHR2972 Castor Oil pharmaceutical secondary standard, certified reference material 8001-79-4 3X200MG ₹34140 2022-06-14 Buy
Sigma-Aldrich(India) C9606 Castor oil meets testing specifications per USP 8001-79-4 1L ₹23139 2022-06-14 Buy
Sigma-Aldrich(India) 259853 Castor oil 8001-79-4 1L ₹4321 2022-06-14 Buy
Sigma-Aldrich(India) 83912 Castor oil tested according to Ph. Eur. 8001-79-4 1L ₹14121 2022-06-14 Buy
Product number Packaging Price Buy
C9606 500ML ₹22860 Buy
PHR2972 3X200MG ₹34140 Buy
C9606 1L ₹23139 Buy
259853 1L ₹4321 Buy
83912 1L ₹14121 Buy

Castor oil Chemical Properties,Uses,Production

Chemical Properties

Dehydrated castor oil is a castor oil from which approximately 5% of the chemically combined water has been removed. Therefore it has drying properties similar to those of Tung oil. Dehydration is carried out by heating the oil in the presence of catalysts such as sulphuric acid, phosphoric acid, clays and metal oxides. Dehydrated castor oil is a yellow oily liquid with characteristic odour.
Standard specifications
commercial grade pale grade special grade
refractive index (20°C) 1,482 - 1,483 1,482 - 1,483 1,482 - 1,483
specific gravity (15°C) 0,982 - 0,933 0,982 - 0,933 0,982 - 0,933
viscosity (25°C) Poise 1,6 - 2,8 1,6 - 2,8 1,6 - 2,8
viscosity Gardner scale G – I G – I G – I
colour max. 8 max. 6 max. 5
acid value mg KOH/g max.6 max. 4
iodine value (Wijs) g I2/100g min. 130 min. 130 min. 130
hydroxyl value mg KOH/g max. 25 max. 20

Physical properties

The oil is a pale-yellowish or almost colorless, transparent viscid liquid. It is soluble in alcohol, and is miscible with absolute alcohol, glacial acetic acid, chloroform and ether.

Occurrence

Castor is a perennial found in India and Africa.

Uses

castor oil is a highly emollient carrier oil that penetrates the skin easily, leaving it soft and supple. It also serves to bind the different ingredients of a cosmetic formulation together. Castor oil is high in glycerin esters of ricinoleic acid (an unsaturated fatty acid). It is rarely, if ever, associated with irritation of the skin or allergic reactions. It is obtained through cold-pressing from seeds or beans of the Ricinus communis (castor oil) plant. Impure castor oil may cause irritation, as the seeds contain a toxic substance that is eliminated during processing. Its unpleasant odor makes it difficult to use in cosmetics.

Indications

Castor oil is a bland oil that is hydrolyzed in the gut to yield ricinoleic acid, the active purging agent. This hydrolysis requires bile, a fact that is sometimes overlooked when castor oil is given as a laxative before radiography in biliary obstruction.The ricinoleic acid acts on the ileum and colon to induce an increased fluid secretion and colonic contraction.

Definition

castor oil: A pale-coloured oil extractedfrom the castor-oil plant. Itcontains a mixture of glyceridesof fatty acids, the predominantacid being ricinoleic acid,C17H32(OH)COOH. It is used as adrying oil in paints and varnishesand medically as a laxative.

Production Methods

Castor oil is the fixed oil obtained by cold-expression of the seeds of Ricinus communis Linne (Fam. Euphorbiaceae). No other substances are added to the oil.

Essential oil composition

The oil is a mixture of triglycerides of which 75 to 90% is ricinoleic acid.* This mixture is hydrolyzed to release ricinoleic acid, which exerts a cathartic effect. The cake remaining after the extraction of the oil is the castor pomace. The phytotoxins ricin and ricinine are found in the seed cake and oil. Ricin is a glycoproptein containing neutral A chain and acidic B chain connected by disulfur bonds.

General Description

Pale-yellow or almost colorless transparent viscous liquid with a faint mild odor and nauseating taste. Density 0.95 g / cm3. A mixture of glycerides, chiefly ricinolein (the glyceride of ricinoleic acid) .

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Castor oil can develop heat spontaneously in the air. [Hawley]. Reacts with acids to liberate heat along with alcohols and acids. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides.

Hazard

Undergoes spontaneous heating.

Health Hazard

If ingested causes severe diarrhea.

Fire Hazard

Castor oil is combustible.

Pharmaceutical Applications

Castor oil is widely used in cosmetics, food products, and pharmaceutical formulations. In pharmaceutical formulations, castor oil is most commonly used in topical creams and ointments at concentrations of 5–12.5%. However, it is also used in oral tablet and capsule formulations, ophthalmic emulsions, and as a solvent in intramuscular injections.
Therapeutically, castor oil has been administered orally for its laxative action, but such use is now obsolete.

Clinical Use

Castor oil is a bland oil that is hydrolyzed in the gut to yield ricinoleic acid, the active purging agent. This hydrolysis requires bile, a fact that is sometimes overlooked when castor oil is given as a laxative before radiography in biliary obstruction.

Safety Profile

An allergen. A human skin and eye irritant. Combustible when exposed to heat. Spontaneous heating may occur. To fight fire, use CO2, dry chemical, fog, mist. See also CASTOR BEAN.

Safety

Castor oil is used in cosmetics and foods and orally, parenterally, and topically in pharmaceutical formulations. It is generally regarded as a relatively nontoxic and nonirritant material when used as an excipient.
Castor oil has been used therapeutically as a laxative and oral administration of large quantities may cause nausea, vomiting, colic, and severe purgation. It should not be given when intestinal obstruction is present.
Although widely used in topical preparations, including ophthalmic formulations, castor oil has been associated with some reports of allergic contact dermatitis, mainly to cosmetics such as lipsticks.

storage

Castor oil is stable and does not turn rancid unless subjected to excessive heat. On heating at 3008℃ for several hours, castor oil polymerizes and becomes soluble in mineral oil. When cooled to 08℃, it becomes more viscous.
Castor oil should be stored at a temperature not exceeding 258℃ in well-filled airtight containers protected from light.

Incompatibilities

Castor oil is incompatible with strong oxidizing agents.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (IM injections; ophthalmic emulsions; oral capsules and tablets; topical creams, emulsions, ointments, and solutions). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Global( 812)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Vedzon Healthcare Pvt Ltd +91-9322176000 +91-9322176000 Maharashtra, India 51 58 Inquiry
Murli Krishna Exports Pvt Ltd +91-2225631595 +91-2225631594 New Delhi, India 185 58 Inquiry
Ultra Chemical Works +91-9820078105 +91-9820078105 Mumbai, India 124 58 Inquiry
Venus Ethoxyethers Pvt Ltd +91-8322383333 +91-8669968881 GOA, India 19 58 Inquiry
Sree Rayalaseema HI Strength Hypo Ltd +91-9848867692 +91-9848867692 Andhra Pradesh, India 19 58 Inquiry
AOS Products Pvt Ltd +91-8285111618 +91-8285111618 Uttar Pradesh, India 76 58 Inquiry
Expo Essential Oils +919210059326 New Delhi, India 72 58 Inquiry
Ghanshyam Chemicals +91-7210130135 +91-9824087558 Gujarat, India 20 58 Inquiry
Kisan Agro +91-2742260262 +91-2742257062 Gujarat, India 5 58 Inquiry
Arvalli Castor Derivatives Pvt Ltd +91-9898002809 +91-9898003829 Vadodara, India 9 58 Inquiry

Related articles

  • Castor Oil: Properties and Uses
  • Castor oil is obtained from castor beans by pressing. This vegetable oil is colorless to pale yellow in color with a peculiar ....
  • Nov 21,2019
CASTOR OIL CASTOR OIL DAB-10 CASTOR OIL(DEHYDRATE) FEMA 2263 CASTOR OIL FCC CASTOR OIL REFINED, PURISS.,PH-QUALITY Castor oil, oxidized RICINI OIL RICINI OLEUM RICINIUS OIL RICINUS OIL OIL OF CASTOR aromaticcastoroil castoroilaromatic cosmetol crystalo goldbond huiledericin nci-c55163 neoloid oilofpalmachristi oliodiricino phorbyol ricirusoil tangantanganoil Ricinus oil Oil of palma christi CASTOR OIL (RICINUS COMMUNIS L.) CASTOR-OIL, PH EUR CASTOR OIL USP ImmersionOilForMicroscopy-OpticallyClear,Non-Fluorescent CASTOR OIL, PHARMA CASTOR OIL, COLD PRESSED Castor oil,medical Castor oil, Eur. Pharm. Grade ricini oleum virginale CASTOROIL,USP(BULK CASTOROIL(FOODGRADEQUALITY) RIZINUSOEL RAFFINIERT Castor oil,Ricini oleum virginale Castor oil 500GR Castor (Ricinus coMMunis) Oil tor oil Castor Oil BP (use for Injection Grade) Costor Oil Castor oil in stock Factory Castor oil Joyce 2,3-bis[[(Z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (Z)-12-hydroxyoctadec-9-enoate Castor Oil, Technical Grade Venelex Xenaderm Castor oil,AR hot selling Castor oil Castor oil USP/EP/BP Oil castor Ricinum communis oil Casstor Oil CASTOR SEED OIL Castor oil, equivalent to USP