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ChemicalBook > Product Catalog >Organic Chemistry >Ketones >2-AMINO-5-FLUOROACETOPHENONE

2-AMINO-5-FLUOROACETOPHENONE

2-AMINO-5-FLUOROACETOPHENONE Structure
CAS No.
2343-25-1
Chemical Name:
2-AMINO-5-FLUOROACETOPHENONE
Synonyms
1-(2-AMino-5-fluorophenyl)ethanone;1-(2-amino-5-fluorophenyl)ethan-1-one;1-(2-Amino-5-fluorophenyl);2-AMINO-5-FLUOROACETOPHENONE;5-Fluoro-2-Amino-Acetophenone;Ethanone, 1-(2-amino-5-fluorophenyl)-
CBNumber:
CB52451184
Molecular Formula:
C8H8FNO
Molecular Weight:
153.15
MOL File:
2343-25-1.mol
Modify Date:
2023/1/11 10:46:38
Request For Quotation

2-AMINO-5-FLUOROACETOPHENONE Properties

Melting point 64-65 °C
Boiling point 264.2±20.0 °C(Predicted)
Density 1.201±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 2.37±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P280-P301+P312-P362+P364
HS Code  2914790090

2-AMINO-5-FLUOROACETOPHENONE Chemical Properties,Uses,Production

Uses

2-Amino-5-fluoroacetophenone can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis

Synthesis_2343-25-1
600 g of 2-ethynyl-4-fluoroaniline and 4 L of water were added to the reaction flask, and then 476 g of hydrochloric acid (concentration: 35%) was added, and thereaction was carried out at 50 ??C for 36 hours.After the reaction, the temperature is lowered to 20-25 ??C, the reaction solution is adjusted to pH 8-9 with 50% sodium hydroxide solution, thetemperature is controlled to not exceed 30 ??C during pH adjustment, and the filter cake is washed with 1 L of water and decompressed at 50 ??C. After drying for 12 h, 622 g of pale yellow solid was obtained, yield91.4%.HPLC purity was 99.2%.

2-AMINO-5-FLUOROACETOPHENONE Preparation Products And Raw materials

Raw materials

2-Amino-5-fluorobenzoic acid 2-Ethynyl-4-fluoroaniline 2-Amino-5-fluorobenzonitrile Methyllithium Methylmagnesium Bromide
4-Fluoroacetanilide Acetonitrile 4-Fluoroaniline Methylmagnesium chloride
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Preparation Products

2-AMINO-5-FLUOROACETOPHENONE Suppliers

Global( 87)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Clarity Research Laboratory +91-8008229325 +91-8008229325 Telangana, India 96 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Masteam Bio-tech Co., Ltd. +86-15200345168 +86-15200345168 CHINA 153 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 7621 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21149 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34571 58 Inquiry
Win-Win chemical CO., Limited +86-0086-577-64498589 +86-15355981851 China 14351 58 Inquiry
Blocksynth Pharmaceutical Technology Co.,Ltd 0086-19817745290; +8619817745290 China 5660 58 Inquiry
Supplier Advantage
Clarity Research Laboratory 58
A.J Chemicals 58
Masteam Bio-tech Co., Ltd. 58
Capot Chemical Co.,Ltd. 60
Jinan Carbotang Biotech Co.,Ltd. 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 58
Career Henan Chemica Co 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Win-Win chemical CO., Limited 58
Blocksynth Pharmaceutical Technology Co.,Ltd 58

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1-(2-Amino-5-fluorophenyl) 2-AMINO-5-FLUOROACETOPHENONE Ethanone, 1-(2-amino-5-fluorophenyl)- 1-(2-amino-5-fluorophenyl)ethan-1-one 1-(2-AMino-5-fluorophenyl)ethanone 5-Fluoro-2-Amino-Acetophenone 2343-25-1