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Methylmagnesium chloride

Methylmagnesium chloride  Structure
CAS No.
676-58-4
Chemical Name:
Methylmagnesium chloride
Synonyms
CH3MgClinTHF;chloromethyl-magnesiu;Methylchloromagnesium;METHYLMAGNESIUM CHLORIDE;Magnesium, chloromethyl-;Methyl(chloro) magnesium;Magnesium carbanide chloride;Methylmagnesium chloride 3.0 M;METHYLMAGNESIUM CHLORIDE IN TFE;Methylmagnesiumchloride,3MinTHF
CBNumber:
CB9774414
Molecular Formula:
CH3ClMg
Molecular Weight:
74.79
MOL File:
676-58-4.mol
MSDS File:
SDS
Modify Date:
2024/7/29 15:17:36

Methylmagnesium chloride Properties

Boiling point 66 °C
Density 1.013 g/mL at 25 °C
Flash point −1 °F
storage temp. Store below +30°C.
solubility Miscible with diethyl ether and tetrahydrofuran.
form Liquid
color Pale brown to dark green
Water Solubility reacts
Sensitive Air & Moisture Sensitive
BRN 3587199
Exposure limits ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
CAS DataBase Reference 676-58-4(CAS DataBase Reference)
EPA Substance Registry System Magnesium, chloromethyl- (676-58-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H261-H318-H225-H260-H302-H314-H335-H351
Precautionary statements  P305+P351+P338-P309-P310-P210-P231+P232-P280-P370+P378-P402+P404-P403+P235-P231+232
Hazard Codes  F,C
Risk Statements  11-14/15-34-19-15-37-14
Safety Statements  26-30-36/37/39-43-45-7/8-33-29-16
RIDADR  UN 3399 4.3/PG 2
WGK Germany  1
1-3-10
Autoignition Temperature 609 °F
TSCA  Yes
HazardClass  4.3
PackingGroup  I
HS Code  29319090
NFPA 704
3
3 2
W

Methylmagnesium chloride price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 189901 Methylmagnesium chloride solution 3.0?M in THF 676-58-4 100ML ₹6992.95 2022-06-14 Buy
Sigma-Aldrich(India) 189901 Methylmagnesium chloride solution 3.0?M in THF 676-58-4 100ML ₹6992.95 2022-06-14 Buy
Sigma-Aldrich 189901 Methylmagnesium chloride solution 3.0?M in THF 676-58-4 4X25ML ₹11214.7 2022-06-14 Buy
Sigma-Aldrich(India) 189901 Methylmagnesium chloride solution 3.0?M in THF 676-58-4 4X25ML ₹11214.7 2022-06-14 Buy
Sigma-Aldrich 189901 Methylmagnesium chloride solution 3.0?M in THF 676-58-4 800ML ₹29086.78 2022-06-14 Buy
Product number Packaging Price Buy
189901 100ML ₹6992.95 Buy
189901 100ML ₹6992.95 Buy
189901 4X25ML ₹11214.7 Buy
189901 4X25ML ₹11214.7 Buy
189901 800ML ₹29086.78 Buy

Methylmagnesium chloride Chemical Properties,Uses,Production

Chemical Properties

dark brown solution

Uses

Methylmagnesium chloride is used as a Grignard reagent and an alkylating agent in organic synthesis.

Definition

ChEBI: Methylmagnesium chloride is an alkylmagnesium halide and a one-carbon compound. available as a solutionin tetrahydrofuran.

Application

Methylmagnesium chloride solution (3 M in THF) undergoes 1,3-addition with dialdose derived nitrones to form N-benzylhydroxylamines. The reductive cleavage of the N-O bond of these N-benzylhydroxylamines results in N-benzylaminosugars, which are key moieties of bioactive compounds. It can also react with Garner type aldehydes to form the corresponding secondary alcohols.

Preparation

reaction of methyl chloride and magnesium in anhydrous diethyl ether, usually in the presence of an initiator.

Reactions

Methylmagnesium chloride can react with acidic hydrogen on oxygen, sulfur and alkyne carbon of compounds containing active hydrogen (such as water, alcohol, mercaptan, amine, amide, acid, sulfonic acid, etc.); Propyl bromide, etc.) undergoes a coupling reaction; it can react with oxygen and carbon dioxide, aldehydes, ketones, etc.

Hazard

Flammable, dangerous fire and explosionrisk.

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Methylmagnesium chloride solution 3.0 M in THF chloromethyl-magnesiu METHYLMAGNESIUM CHLORIDE METHYLMAGNESIUM CHLORIDE, 2.5M SOLUTIONIN BUTYL DIGLYME METHYLMAGNESIUM CHLORIDE, 3.0M SOLUTION IN TETRAHYDROFURAN METHYLMAGNESIUM CHLORIDE SOLUTION, ~3 M IN THF METHYLMAGNESIUM CHLORIDE, 3.0M SOLUTION Methylmagnesium chloride solution technical, ~3 M in THF Methylmagnesium chloride, 22 wt% solution in tetrahydrofuran, AcroSeal MethylMagnesiuM chloride, 3M (22 wt.%) solution in THF, AcroSeal Methylmagnesium chloride solution, 3.0 M solution in THF, HySeal METHYL MAGNESIUM CHLORIDE 22% in THF or 3M in THF Methylmagnesium chloride 1M solution in 2-MeTHF Methylmagnesium chloride 1M solution in Cyclopentyl methyl ether Methylmagnesium chloride 1M solution in Di-n-butyl ether Methylmagnesium chloride 3M solution in THF MethylMagnesiuM chloride, 3.0 M solution in THF, J&KSeal MethylMagnesiuM chloride, 3.0 M solution in THF, SpcSeal Methylmagnesium chloride, 22 wt% solution in tetrahydrofuran METHYLMAGNESIUM CHLORIDE IN TFE Magnesium, chloromethyl- methylmagnesium chloride solution methylmagnesium chloride, 3m in thf, packaged under argon in resealable chemseal Methylmagnesium Chloride 1.5 M In Butyl Diglyme Methylmagnesium Chloride 1.5 M in n-Butyl Ether Methylmagnesium Chloride 2.0 M In Diethyl Ether Methylmagnesium Chloride 2.0 M In Tetrahydrofuran Methylmagnesium Chloride 2.2 M In Butyl Diglyme Methylmagnesium Chloride 3.0 M In Tetrahydrofuran Methylmagnesiumchloride,3MinTHF Methylmagnesium chloride, 3M in THF, packaged under Argon in resealable ChemSealTM bottles Methylmagnesium chloride, 3M in THF, packaged under Argon in resealable ChemSeal bottles Magnesium carbanide chloride Methylmagnesium chloride22 wt% solution in tetrahydrofuranAcroSeal§3 Methyl(chloro) magnesium Methylchloromagnesium Methylmagnesium chloride, 3M in THF, packaged under Argon in resealable ChemSeal^t bottles METHYLMAGNESIUM CHLORIDE, 3 M in TETRAHYDROFURAN Methulmagnesium chloride solution Methylmagnesium chloride [3.0 M sulution in THF] M**METHYLMAGNESIUM CHLORIDE 3.0M SOLUTION THF CH3MgClinTHF Methylmagnesium chloride 3.0 M Methylmagnesium chloride solution( 3.0 M solution in THF) Methylmagnesium chloride, 2.5 M solution in THF, J& Methylmagnesium chloride(3M THF) Methylmagnesium chloride 3.0 M solution in THF Methyl Magnesium Chloride (3.0 M in THF) Methylmagnesium Chloride 3.0M In THF / 3.2M In 2METHF METHYLMAGNESIUM CHLORIDE 3.0M THF/3.2M 2MeTHF METHYL MAGNESIUM CHLORIDE 3 MOLAR IN THF Methyl Magnesium Chloride 3 Molar Solution in Tetrahydrofuran Methyl magnesium chloride solution (3 M THF) 676-58-4 676-85-4 CH3ClMg CH3MgCl Organometallic Reagents