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ARZOXIFENE

ARZOXIFENE Structure
CAS No.
182133-25-1
Chemical Name:
ARZOXIFENE
Synonyms
SERMIII;ARZOXIFENE;2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol;2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]benzo[b]thiophene-6-ol;Benzo[b]thiophene-6-ol, 2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]-;3-[(4-{[2-(hexahydropyridin-1-yl)ethyl]oxy}phenyl)oxy]-2-(4-methoxyphenyl)benzo[b]thiophen-6-ol
CBNumber:
CB52451290
Molecular Formula:
C28H29NO4S
Molecular Weight:
475.6
MOL File:
182133-25-1.mol
MSDS File:
SDS
Modify Date:
2025/4/17 18:22:24
Request For Quotation

ARZOXIFENE Properties

Melting point 174-176°
Boiling point 656.4±55.0 °C(Predicted)
Density 1.234
pka 9.20±0.40(Predicted)

ARZOXIFENE Chemical Properties,Uses,Production

Clinical Use

Arzoxifene is a third-generation SERM currently in Phase III clinical trials for the treatm ent of ER-positive recurrent/metastatic breast cancer. Similar to raloxifene, it is an ER antagonist in both breast and uterine tissues and an ER agonist on bone and the cardiovascular system. Arzoxifene is able to both preserve and build bone mineral density, which makes it a viable candidate for the treatment of osteoporosis. Ample evidence from early clinical trials indicates that arzoxifene also can be utilized as a chemopreventive agent against breast cancer.

Side effects

Adverse effects include hot flashes (major) and headache, nausea, vomiting, and constipation (minor).

ARZOXIFENE Preparation Products And Raw materials

Raw materials

Preparation Products

ARZOXIFENE Suppliers

Global( 22)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49734 58 Inquiry
Beijing Fuchen Technology Co., Ltd 15652759959 China 337 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24719 58 Inquiry
BOC Sciences 1-631-485-4226; 16314854226 United States 12952 65 Inquiry
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 China 18478 58 Inquiry
NE Scientific +1 (617) 651-6662 United States 5030 55 Inquiry
Beijing Yisiyan Technology Research Center 010-56645598 13366904824 China 1641 59 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6650 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
CONIER CHEM AND PHARMA LIMITED 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Beijing Fuchen Technology Co., Ltd 58
TargetMol Chemicals Inc. 58
BOC Sciences 65
Changzhou Bojia Biomedical Technology Co., Ltd. 58
NE Scientific 55
Beijing Yisiyan Technology Research Center 59
Shanghai Hao Zhun Biological Technology Co., Ltd. 58

182133-25-1(ARZOXIFENE)Related Search:

2-(4-METHOXY PHENYL)BENZOTHIOPHENE-6-OL 4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENOL 2-(4-Methoxyphenyl)benzothiophene ARZOXIFENE
ARZOXIFENE 2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]benzo[b]thiophene-6-ol Benzo[b]thiophene-6-ol, 2-(4-Methoxyphenyl)-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]- 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol 3-[(4-{[2-(hexahydropyridin-1-yl)ethyl]oxy}phenyl)oxy]-2-(4-methoxyphenyl)benzo[b]thiophen-6-ol SERMIII 182133-25-1