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3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-

3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Structure
CAS No.
290297-25-5
Chemical Name:
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-
Synonyms
Netupitant N-1;Netupitant ITS-3;N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine;N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-ami...;methyl-[6-(4-methyl-piperazin-1-yl)-4-o-tolyl-pyridin-3-yl]-amine;N-methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-amine;N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine;N-Methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)-3-aminopyridine;3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-;N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine acid
CBNumber:
CB52456457
Molecular Formula:
C18H24N4
Molecular Weight:
296.41
MOL File:
290297-25-5.mol
MSDS File:
SDS
Modify Date:
2023/6/8 18:36:12
Request For Quotation

3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Properties

Boiling point 478.2±45.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
pka 9.73±0.38(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Chemical Properties,Uses,Production

Uses

N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine is used as a reactant in the synthesis of NK1 receptor antagonists via 1,4-Grignard addition/oxidation sequence to 6-chloronicotinic acid and derivatives.

3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Preparation Products And Raw materials

Raw materials

3-PYRIDINECARBOXAMIDE, N-(1,1-DIMETHYLETHYL)-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine 6-CHLORO-4-O-TOLYL-NICOTINAMIDE N-[4-iodo-6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-2,2-dimethyl-propionamide 6-CHLORO-4-O-TOLYL-NICOTINIC ACID
N-(6-(4-Methylpiperazin-1-yl)pyridin-3-yl)pivalaMide N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide 2-(4-Methylpiperazin-1-yl)-5-nitropyridine O-TOLYLMAGNESIUM CHLORIDE Methyl (6-(4-Methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)carbaMate
3-PYRIDINECARBOXAMIDE, 4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- 2-Chloro-5-nitropyridine 1-Methylpiperazine 6-Chloronicotinic acid
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Preparation Products

3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Suppliers

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ANHUI WITOP BIOTECH CO., LTD 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
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Hefei TNJ Chemical Industry Co.,Ltd. 58
Coresyn Pharmatech Co., Ltd. 58
Changzhou Rokechem Technology Co., Ltd. 58
GIHI CHEMICALS CO.,LIMITED 58
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd. 58

290297-25-5(3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-)Related Search:

2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide Methyl (6-(4-Methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)carbaMate 3-PYRIDINECARBOXAMIDE, 4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide 1-(3-AMINO-PYRIDIN-4-YL)-ETHANONE
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-
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3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Netupitant N-1 N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine methyl-[6-(4-methyl-piperazin-1-yl)-4-o-tolyl-pyridin-3-yl]-amine N-Methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)-3-aminopyridine N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine Oxalic acid N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine acid N-methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-amine N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-ami... Netupitant ITS-3 N-methyl-4- (2-methylphenyl) -6- (4-methyl-1-piperazinyl) -3-pyridine amine 290297-25-5 290297-25-2 290297-25-0 C18H24N4