ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Transmembrane Transporters >Calcium Channel Inhibitors >Benidipine hydrochloride
Benidipine hydrochloride
- CAS No.
- 91599-74-5
- Chemical Name:
- Benidipine hydrochloride
- Synonyms
- (3R)-1-Benzyl-3-piperidinyl methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1);Conipros;Benidipin;rac-Benidipine HCl;Benidipine hydrochlo;Benidipine Impurity 4;Benidipine hydrochloride;rac Benidipine Hydrochloride;Benidipine hydrochloride USP/EP/BP;(R,R)(S,S)-Benidipine Hydrochloride
- CBNumber:
- CB5294563
- Molecular Formula:
- C28H31N3O6.HCl
- Molecular Weight:
- 542.02
- MOL File:
- 91599-74-5.mol
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 199-201°C |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: ≥20mg/mL |
| pka | 7.34(at 25℃) |
| form | powder |
| color | yellow |
| InChIKey | DGVVISBYHUXFIU-UHFFFAOYSA-N |
| CAS DataBase Reference | 91599-74-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | US7975657 | |||||||||
| HS Code | 2933.99.5300 | |||||||||
| Toxicity | LD50 orally in male mice: 218 mg/kg (Muto, 1988) | |||||||||
| NFPA 704 |
|
Benidipine hydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B6813 | Benidipine hydrochloride ≥98% (HPLC) | 91599-74-5 | 10MG | ₹8486.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B6813 | Benidipine hydrochloride ≥98% (HPLC) | 91599-74-5 | 50MG | ₹34098.75 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B5629 | Benidipine Hydrochloride | 91599-74-5 | 100MG | ₹6500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B5629 | Benidipine Hydrochloride | 91599-74-5 | 1G | ₹19500 | 2022-05-26 | Buy |
Benidipine hydrochloride Chemical Properties,Uses,Production
Description
Benidipine hydrochloride is a new, long acting dihydropyridine calcium antagonist useful in the treatment of hypertension and angina pectoris. In experimental animals, benidipine hydrochloride dose dependently induced hypotension with a potency of 6 and 12 times more than nifedipine and nicardipine, respectively. It also exhibited a slow onset of action.
Chemical Properties
Yellow Crystalline Powder
Uses
A dihydropyridine calcium channel blocker. Antihypertensive.
Biological Activity
Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo . Inhibits L-, N- and T-type Ca 2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.
Safety Profile
A poison by ingestion,intraperitoneal, and intravenous routes. When heated todecomposition it emits toxic vapors of NOx and HCl.
Benidipine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 269)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Prayosha Health Care Pvt Ltd | +91-9924448881 +91-9924448881 | Gujarat, India | 15 | 58 | Inquiry |
| Afton Pharma | +91-9712000202 +91-9712000202 | Gujarat, India | 63 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Globela Industry Pvt Ltd | +91-2616158000 +91-9998199919 | Gujarat, India | 98 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Steris Healthcare Private Limited | 08048967517 | Mumbai, India | 10 | 58 | Inquiry |
| Chemizo Enterprise | 08048961375 | Ahmedabad, India | 29 | 58 | Inquiry |
91599-74-5(Benidipine hydrochloride)Related Search:
(R,R)-(+/-)-2,6-DIMETHYL-4-(3-NITROPHENYL)-1,4-DIHYDRO-3,5-PYRIDINE,DICARBOXYLIC ACID METHYL-1-BENZYL-3-PIPERIDYL-ESTER,MONOHYDROCHLORIDE SALT
Coniel, Capadipine, KW-3049, Nacadipine
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl (3R)-1-(phenylmethyl)-3-piperidinyl ester, monohydrochloride, (4R)-rel-
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-(phenylmethyl)-3-piperidinyl ester, monohydrochloride, (R*,R*)-(+-)-
(R,R)-(+/-)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-Dihydro-3,5-pyridine-dicarboxylic acid methyl-1-benzyl-3-piperidyl-ester hydrochloride
Benidipine hydrochloride
monohydrochloride,(r*,r*)-(+-)-hyl1-(phenylmethyl)-3-piperidinyleste
1-(BENZYLMETHYL)-3-PIPERIDINYL 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINEDICARBOLATE
2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-DimethoxyCarboxylate
(R,R)-(+/)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidmethyl-1-(phenylmethyl)-3-piperidiny
Benidipine hydrochlo
(4R)-rel-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester, hydrochloride (1:1)
(4R)-rel-3,5-Pyridinedicarboxylic acid
3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester
Conipros
rac-(4R*)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl 5-[(3R*)-1-benzylpiperidine-3-yl]·hydrochloride
(4R)-rel-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid3-methyl5-[(3R)-1-(phenylmethyl)-3-piperidinyl]esterhydrochloride
rac Benidipine Hydrochloride
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl5-[(3R)-1-(phenylMethyl)-3-piperidinyl] ester, hydrochloride (1:1), (4R)-rel-
rac-Benidipine HCl
Benidipine Impurity 4
3-[(3RS)-1-Benzylpiperidin-3-yl] 5-Methyl (4RS)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Hydrochloride
Benidipine hydrochloride USP/EP/BP
(R)-rel-3-((R)-1-Benzylpiperidin-3-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
5-O-[(3R)-1-benzylpiperidin-3-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate,hydrochloride
(3R)-1-Benzyl-3-piperidinyl methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1)
3-[(R*)-1-Benzylpiperidin-3-yl] (R*)-5-Methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Hydrochloride
Cocaine Hydrochloride Impurity 3(Cocaine Hydrochloride EP Impurity C )(β-Truxilline)
Benidipin
(R,R)(S,S)-Benidipine Hydrochloride
(±)-(R*)-3-[(R*)-1-Benzyl-3-piperidyl]methyl 1,4-dihydro-2,6-dimethyl- 4-(m-nitrophenyl)-3,5-pyridinedicarboxylate hydrochloride
(3R*)-1-Benzylpiperidin-3-yl methyl (4R*)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
91599-74-5
91599-47-5
C28H32ClN3O6
C28H31N3O6
Inhibitors
Antihypertensive
Intermediates & Fine Chemicals
Pharmaceuticals
Aromatics
Chiral Reagents
Heterocycles