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Lacidipine

Lacidipine Structure
CAS No.
103890-78-4
Chemical Name:
Lacidipine
Synonyms
β-GPA;MOTENS;SN-305;LACIREX;LACIPIL;GX-1048;CALDINE;Lacidipin;GR-43659X;LACIDIPINE
CBNumber:
CB5296310
Molecular Formula:
C26H33NO6
Molecular Weight:
455.54
MOL File:
103890-78-4.mol
MSDS File:
SDS
Modify Date:
2023/8/9 17:41:26

Lacidipine Properties

Melting point 174-175°C
Boiling point 558.4±50.0 °C(Predicted)
Density 1.127±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble20mg/mL, clear
pka 3.00±0.70(Predicted)
form powder
color white to beige
Merck 14,5331
InChIKey GKQPCPXONLDCMU-CCEZHUSRSA-N
CAS DataBase Reference 103890-78-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  US7970200
Toxicity mouse,LD50,intraperitoneal,80200ug/kg (80.2mg/kg),SKIN AND APPENDAGES (SKIN): HAIR: OTHERSENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYEBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22, Pg. 335, 1994.
NFPA 704
0
1 0

Lacidipine price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0946 Lacidipine ≥98% (HPLC) 103890-78-4 10MG ₹8605.88 2022-06-14 Buy
Sigma-Aldrich(India) SML0946 Lacidipine ≥98% (HPLC) 103890-78-4 50MG ₹34878.15 2022-06-14 Buy
TCI Chemicals (India) L0276 Lacidipine 103890-78-4 1G ₹19600 2022-05-26 Buy
Product number Packaging Price Buy
SML0946 10MG ₹8605.88 Buy
SML0946 50MG ₹34878.15 Buy
L0276 1G ₹19600 Buy

Lacidipine Chemical Properties,Uses,Production

Description

Lacidipine is a new second-generation dihydropyridine calcium antagonist introduced as a once a day treatment for mild to moderate hypertension. It is reported to have high selectivity for vascular smooth muscle and also a long duration of action. The use of lacidipine as an antiatherosclerotic agent is currently under investigation.

Chemical Properties

White-to-Off-White Crystalline Solid

Lacidipine Preparation Products And Raw materials

Raw materials

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Preparation Products

Global( 352)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Dr. Reddy's Laboratories Ltd +91-4049002900 +91-4049002900 Hyderabad, India 165 58 Inquiry
KARPSCHEM LABORATORIES +91-7249203006 +91-7249203006 Maharashtra, India 786 58 Inquiry
Unichem Laboratories Ltd +91-2266888333 +91-2266888333 Maharashtra, India 62 58 Inquiry
Pharmaffiliates Analytics & Synthetics (P) Ltd. 91-172-5066494 Haryana, India 631 58 Inquiry
Aarti Healthcare Limited + 91 22 6797 6666 Mumbai, India 28 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Dazzle Corporation 91-22-28878459 Maharashtra, India 209 58 Inquiry
Unichem Laboratories Ltd. 91-22-66888333 Maharashtra, India 35 58 Inquiry
Athos Chemicals 91-9998858909 Gujarat, India 315 58 Inquiry
Parth Overseas 91-22-28802773 Maharashtra, India 50 58 Inquiry

Lacidipine Spectrum

3,5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylet diethylester,(e)-hoxy)-3-oxo-1-propenyl)phenyl) MOTENS 3,5-Diethyl 4-{2-[(1E)-3-(tert-butoxy)-3-oxoprop-1-en-1-yl]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate CID 5311217 Lacidipine,Lacipil 4-[2-[(1E)-3-(1,1-dimethylethoxy)-3-oxo-1-propen-1-yl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-diethyl ester GX-1048,GR-43659X,SN-305 LACIPIL LACIREX LACIDIPINE LACIDIPINE-D9 Lacidipin LACIDIPINE, IMPURITY STANDARD BP STANDARD LACIDIPINE, BP STANDARD LACIDIPINE ASSAY STANDARD BP(CRM STANDARD) LACIDIPINE BP STANDARD(CRM STANDARD) LACIDIPINE IMPURITY STANDARD BP STANDARD(CRM STANDARD) LACIDIPINE IMPURITY STANDARD BP(CRM STANDARD) LacidipineC26H33N06 GX-1048 GR-43659X CALDINE (E)-4-[2-[3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL]PHENYL]-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER (E)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester, GR-43659X, GX-1048, Caldine, Lacipil, Lacirex, Motens trans Lacidipine Lacidipine (Lacipil, Motens) 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylethoxy)-3-oxo-1- propenyl)phenyl)-, diethyl ester, (E)- Diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate 4-[2-[(1E)-3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester 4-[2-[(E)-3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester SN-305 Lacidipine Solution, 100ppm Lacidipine Solution, 1000ppm LACIPIL;MOTENS 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester 3,5-Pyridinedicarboxylic acid, 4-[2-[(1E)-3-(1,1-dimethylethoxy)-3-oxo-1-propen-1-yl]phenyl]-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester Lacidipine USP/EP/BP (E)-Diethyl 4-(2-(3-(tert-butoxy)-3-oxoprop-1-en-1-yl)phenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Lacidipine (GX-1048, GR-43659X, SN-305, Lacipil, Motens) LacidipineQ: What is Lacidipine Q: What is the CAS Number of Lacidipine Q: What is the storage condition of Lacidipine Q: What are the applications of Lacidipine β-GPA Lacidipine flat Lacipil, Motens, Lacidipine iethyl2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate Lacidipine Diethyl 4-{o-[(E)-2-tert-butoxycarbonylethenyl]phenyl}-2,6- dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 103890-78-4 C26H33NO6 C26H24NO6D9 Calcium channel Dihydropyridine Intermediates & Fine Chemicals Pharmaceuticals Active Pharmaceutical Ingredients Dihydropyridine Class Chemicals API Lacipil, Motens