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Aprepitant Impurity 9

Aprepitant Impurity 9 Structure
CAS No.
219821-37-1
Chemical Name:
Aprepitant Impurity 9
Synonyms
Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber:
CB53358992
Molecular Formula:
C24H25F7N4O4
Molecular Weight:
566.47
MOL File:
219821-37-1.mol
Modify Date:
2023/5/15 10:44:00
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Aprepitant Impurity 9 Properties

Density 1.43±0.1 g/cm3(Predicted)
solubility soluble in Chloroform, Dichloromethane, Methanol
form Solid
pka 7.86±0.43(Predicted)
color Pale-Yellow

Aprepitant Impurity 9 Chemical Properties,Uses,Production

Uses

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 Preparation Products And Raw materials

Raw materials

N-Benzylethanolamine

Preparation Products

Aprepitant

Aprepitant Impurity 9 Suppliers

Global( 36)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Labnetwork lnc. +86-27-50766799 +8618062016861 China 19994 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 China 5000 58 Inquiry
Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 China 10951 58 Inquiry
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 18502726233; 18502726233 China 9486 58 Inquiry
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 China 9911 50 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
Pharma Affiliates 58
Labnetwork lnc. 58
China National Standard Pharmaceutical Corporation Limited 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 58
Guangzhou Juntang Technology Co., Ltd 58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 58
Shanghai Kewel Chemical Co., Ltd. 50

219821-37-1(Aprepitant Impurity 9)Related Search:

Aprepitant-M3 Metabolite 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Aprepitant Aprepitant Impurity 6 Fosaprepitant Impurity 6
5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Aprepitant (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Aprepitant Impurity 17 (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
Fosaprepitant Benzyl Ester [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Defluoro Aprepitant Aprepitant Impurity A Enantiomer
5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2
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Aprepitant Impurity 9 Aprepitant Open-Ring Methyl Ester Impurity 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity Aprepitant Impurity 47 Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate Fosaprepitant Impurity U 219821-37-1 C24H25F7N4O4