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1400W

CAS No.: 180001-34-7

Chemical Name:: 1400W

Synonyms: 1400W DIHYDROCHLORIDE;400W;1400W;W 1400;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE;N-(3-(aminomethyl)benzyl)acetimidamide;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL;Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]-;N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE;N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE

CBNumber:: CB5343313

Molecular Formula:: C10H15N3

Molecular Weight:: 177.25

MOL File:: 180001-34-7.mol

Modify Date:: 2023/5/4 17:34:35

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1400W Properties

Melting point	208-220 °C
Boiling point	301.7±44.0 °C(Predicted)
Density	1.09±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	DMSO, Methanol, Water
pka	11.33±0.50(Predicted)
form	solid
color	White to Off-White

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

1400W Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

1400W selectively inhibits inducible nitric oxide synthase. W 1400 has been implicated to prevent Doxorubicin and Trastuzumab induced cardiotoxicity.

Biological Activity

Slow, tight binding, potent and highly selective inhibitor of inducible nitric oxide synthase (K d = 7 nM). Selective over nNOS and eNOS (K i values are 2 and 50 μ M respectively). Cell-permeable and active in vivo .

1400W Preparation Products And Raw materials

Raw materials

Preparation Products

1400W Suppliers

Global( 61)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Hebei Int'en Pharmaceutical Technology Co., Ltd	18932921510	China	2102	58	Inquiry
Chunchuang (Wuhan) Technology Co., Ltd	15342225168	China	10006	58	Inquiry
Shanghai Tachizaki Biomedical Research Center	18014399201	China	2497	58	Inquiry
Shanghai Yuda Industrial Co., Ltd.	021-64133189 13788995069	CHINA	6107	58	Inquiry
Shanghai Yuqi Biological Technology Co., Ltd.	18930788570	CHINA	6087	58	Inquiry
Shanghai Jingke Chemical Technology Co., Ltd.	021-54997581 13524423207	CHINA	6974	58	Inquiry
Beijing Anbiqi Biotechnology Co., Ltd.	15811277462	CHINA	2529	58	Inquiry
Shenzhen Branch Science and Technology Co., Ltd.	0755-33164177 13924667705	CHINA	6478	58	Inquiry

Supplier	Advantage
career henan chemical co	58
Zhejiang J&C Biological Technology Co.,Limited	58
Hebei Int'en Pharmaceutical Technology Co., Ltd	58
Chunchuang (Wuhan) Technology Co., Ltd	58
Shanghai Tachizaki Biomedical Research Center	58
Shanghai Yuda Industrial Co., Ltd.	58
Shanghai Yuqi Biological Technology Co., Ltd.	58
Shanghai Jingke Chemical Technology Co., Ltd.	58
Beijing Anbiqi Biotechnology Co., Ltd.	58
Shenzhen Branch Science and Technology Co., Ltd.	58

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1400W N-[[3-(AMINOMETHYL)PHENYL]METHYL]-ETHANIMIDAMIDE DIHYDROCHLORIDE N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE 2HCL N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE, DIHYDROCHLORIDE 400W W 1400 Ethanimidamide, N-[[3-(aminomethyl)phenyl]methyl]- 1400W DIHYDROCHLORIDE N-(3-(aminomethyl)benzyl)acetimidamide 180001-34-7 18001-34-7 Biochemicals and Reagents BioChemical Application Index Cell Signaling Enzymes NOS Inhibitors Enzymes, Inhibitors, and Substrates Nitric Oxide Metabolism Nitric Oxide Reagents Nitric Oxide Aromatic Building Blocks Signalling