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CAPSANTHIN

CAPSANTHIN Structure
CAS No.
465-42-9
Chemical Name:
CAPSANTHIN
Synonyms
Paprika Red;Yellow corn;CAPSANTHIN/CAPSORUBIN;E 160c;C08584;Chili Red;CAPSANTHIN;CAPSORUBINE;Capsanthine;CAPSANTHIN tlc
CBNumber:
CB5380132
Molecular Formula:
C40H56O3
Molecular Weight:
584.87
MOL File:
465-42-9.mol
MSDS File:
SDS
Modify Date:
2024/5/14 11:56:19

CAPSANTHIN Properties

Melting point 177-178℃
alpha Cd +36° (chloroform)
Boiling point 581.82°C (rough estimate)
Density 1.012
refractive index 1.4960 (estimate)
storage temp. -20°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form Solid
pka 14.85±0.60(Predicted)
color Dark Red to Very Dark Brown
λmax λ: 467-471 nm Amax
Merck 14,1769
Stability Light Sensitive, Temperature Sensitive
LogP 9.467 (est)

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  2914.50.3000

CAPSANTHIN price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 94863 Capsanthin analytical standard 465-42-9 1MG ₹95604.3 2022-06-14 Buy
TCI Chemicals (India) C0781 Capsanthin (=Paprika Extract) (Vegetable oil solution) 465-42-9 25G ₹3500 2022-05-26 Buy
Product number Packaging Price Buy
94863 1MG ₹95604.3 Buy
C0781 25G ₹3500 Buy

CAPSANTHIN Chemical Properties,Uses,Production

Description

Capsanthin is a carotenoid that has been found in C. annuum and has diverse biological activities. It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells. Capsanthin (0.2 mg/animal) reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis. It also reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; ).

Uses

Capsanthin may be used as an analytical reference standard for the quantification of the analyte in red pepper powder, red pepper fruits, paprika and oleoresin using chromatography techniques.

General Description

Capsanthin, also known as the red pepper carotenoid, is one of the major color pigments of paprika oleoresin, an oil-soluble extract, isolated from the fruits of Capsicum annum Linn or Capsicum frutescens. It is widely used as a color additive in food industries across the globe. The photoprotective effect of capsanthin protects human dermal fibroblasts against UVB induced DNA damage.

Hazard

A poison by skin contact.

Safety Profile

A poison by skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.

Purification Methods

Possible impurities are zeaxanthin and capsorubin (below). Purify capsanthin by chromatography on a column of alumina (grade IV) and develop with 0.2% EtOH in *C6H6. It

CAPSANTHIN Preparation Products And Raw materials

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PAPRIKA EXTRACT BETA,KAPPA-CAROTEN-6'-ONE, 3,3'-DIHYDROXY-, (3R,3'S,5'R)- CAPSANTHIN 3,3'-DIHYDROXY-BETA,KAPPA-CAROTEN-6'-ONE Capsanthin(=paprika E 160c (3R,3'S,5'R)-3,3'-dihydroxy-beta,.kappa.-caroten-6'-one Chili Red Oleoresin paprika 10-100,000 Cu CAPSORUBINE CAPSANTHIN(=PAPRIKA EXTRACT)(VEGETABLE OIL SOLUTION) CAPSANTHIN:B, |-CAROTEN-6''-ONE, 3,3''-DIHYDROXY-, (3R,3''S,5''R)-, CAPSANTHIN WITH TLC CAPSANTHIN tlc (3R,3'S)-3,3'-Dihydroxy-β,κ-carotene-6'-one (3R,3'S,5'R)-3,3'-Dihydroxy-β,κ-caroten-6'-one all-trans-Capsanthin Capsanthine Capsanthin (=Paprika Extract) C08584 CAPSANTHIN(SH)(IN CHLOROFORM) (all-E)-19-(4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-1-(4-hydroxy-1,2,2-trimethylcyclopentyl)-4,8,13,17-tetramethyl-2,4,6,8,10,12,14,16,18-nonadecanonaen-1-one (=Paprika Extract) (Vegetable oil solution) Capsanthin  Oil soluble capsicum red pigment Oil-soluble red pepper colorant capsanthin (2E,4E,6E,8E,10E,12E,14E,16E,18E)-19-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-1-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethylnonadeca-2,4,6,8,10,12,14,16,18-nonaen-1-one β,κ-Caroten-6'-one, 3,3'-dihydroxy-, (3R,3'S,5'R)- Water-soluble paprika oleoresin Chili red pigment (2E,4E,6E,8E,10E,12E,14E,16E,18E)-19-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-1-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethyl-1-nonadeca-2,4,6,8,10,12,14,16,18-nonaenone CAPSANTHIN/CAPSORUBIN Paprika Red Yellow corn Nicotinamide Impurity 239 465-42-9 C40H56O3 Thiophenes ,Thiazolines/Thiazolidines Carotenoids