Methylene-bis(4-cyclohexylisocyanate)
- CAS No.
- 5124-30-1
- Chemical Name:
- Methylene-bis(4-cyclohexylisocyanate)
- Synonyms
- rmdi;dmdi;smdi;picm;isocyanicacid,methylenedi-4,1-cyclohexyleneester;hylenew;cp99173;4,4'-HMDI;Dicyclohex;reducedmdi
- CBNumber:
- CB5412149
- Molecular Formula:
- C15H22N2O2
- Molecular Weight:
- 262.35
- MOL File:
- 5124-30-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/29 18:52:01
| Melting point | 25°C |
|---|---|
| Boiling point | 168 °C / 1.5mmHg |
| Density | 1.066 g/mL at 25 °C(lit.) |
| vapor pressure | 0.001Pa at 20℃ |
| refractive index |
n |
| Flash point | >230 °F |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless |
| Water Solubility | Insoluble/Reactive |
| BRN | 2217800 |
| Exposure limits | TLV-TWA 0.0535 mg/m3 (0.005 ppm) (ACGIH). |
| Stability | Hygroscopic |
| LogP | 6.11 at 20℃ |
| CAS DataBase Reference | 5124-30-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Cyclohexane, 1,1'-methylenebis[4-isocyanato-(5124-30-1) |
| EPA Substance Registry System | 1,1-Methylene bis(4-isocyanatocyclohexane) (5124-30-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H317-H319-H331-H334-H335 | |||||||||
| Precautionary statements | P261-P264-P280-P302+P352-P304+P340+P311-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23-36/37/38-42/43 | |||||||||
| Safety Statements | 26-28-38-45-1/2 | |||||||||
| RIDADR | UN 2206 6.1/PG 2 | |||||||||
| OEL | Ceiling: 0.01 ppm (0.11 mg/m3) | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | NQ9250000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2929.10.8090 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
Methylene-bis(4-cyclohexylisocyanate) price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 388386 | 4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers 90% | 5124-30-1 | 100ML | ₹5369.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 388386 | 4,4′-Methylenebis(cyclohexyl isocyanate), mixture of isomers 90% | 5124-30-1 | 500ML | ₹12037.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 33490 | HMDI analytical standard | 5124-30-1 | 2ML | ₹6614.08 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D2380 | Dicyclohexylmethane 4,4'-Diisocyanate (mixture of isomers) min. 90.0 %(total of isomer) | 5124-30-1 | 25G | ₹2200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D2380 | Dicyclohexylmethane 4,4'-Diisocyanate (mixture of isomers) min. 90.0 %(total of isomer) | 5124-30-1 | 100G | ₹2900 | 2022-05-26 | Buy |
Methylene-bis(4-cyclohexylisocyanate) Chemical Properties,Uses,Production
Description
Methylene bis (4-cyclohexylisocyanate) (HMDI) (CAS No. 5124-30-1) is a clear to pale yellow liquid, which is soluble in acetone water and is incompatible with alcohols, amines, bases, acids, and may slowly polymerize if heated above 50 ℃. HMDI reacts with water and alcohol.
Chemical Properties
Liquid.Soluble in acetone;reacts with water or ethanol.
Uses
HMDI has excellent light stability and the stability of the six membered ring structure, has excellent weather resistance and excellent mechanical properties of polyurethane material, and is especially suitable for the production of high performance elastic body, a water polyurethane resin and UV resin.
Definition
ChEBI: A diisocyanate consisting of dicyclohexylmethane with two isocyanate groups at the 4- and 4'-positions.
General Description
Clear colorless to light-yellow liquid.
Air & Water Reactions
Reacts with water to form CO2
Reactivity Profile
Isocyanates and thioisocyanates, such as Methylene-bis(4-cyclohexylisocyanate), are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].
Hazard
Strong skin and eye irritant. Respiratorysensitization and lower respiratory tract irritant.
Health Hazard
Studies on test animals indicate that methy-lene bis(4-cyclohexylisocyanate) is highlytoxic by an inhalation route and can causesevere skin reaction. Exposure to 20 ppmfor 5 hours produced irritation of the respiratory tract, tremor, convulsion, congestion oflungs, and edema in rats. The symptoms atlower levels were decreased as to respirationrate and pulmonary irritation.
Contact with the skin can produce severeirritation, erythema, and edema. The oraltoxicity of this compound is very low.
LD50 value, oral (rats): 9900 mg/kg
There is no report of the compound’smutagenicity or carcinogenicity.
Fire Hazard
Flash point data for Methylene-bis(4-cyclohexylisocyanate) are not available. Methylene-bis(4-cyclohexylisocyanate) is probably combustible.
Safety Profile
Poison by inhalation. Mildly toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and CN-.
Potential Exposure
A potential danger to those involved in the manufacture of this compound or its use in the production of light-stable, nonyellowing polyurethane resins.
Environmental Fate
HMDI is a synthetic organic chemical which does not occur naturally in the environment. At room temperature, it is a liquid. HMDI hydrolyzes rapidly in water, producing methylene bis(4-cyclohexylamine). The half-life for HMDI is approximately 2 h. Due to its rapid hydrolysis, transport between environmental compartments is unlikely to occur. Because of the rapid hydrolysis, the assessment of the substance is based on the hydrolysis product methylenebis(cyclohexylamine) and not on HMDI. The hydrolysis product was not classified as a PBT (persistent, bioaccumulative, toxic) substance. These data indicate that HMDI is not readily biodegradable. However, due to its rapid hydrolysis, HMDI is neither persistent in the water compartment nor bioaccumulative. The calculated Koc-value indicates that HMDI may strongly adsorb to soil; however, any emission to the terrestrial compartment would be affected by humidity and, therefore, terrestrial accumulation is not expected to occur.
Shipping
UN2206 Isocyanates, toxic, n.o.s. or Isocyanate solutions, toxic, n.o.s., flash point .61C and boiling point ,300C, Hazard Class: 6.1; Labels: 6.1-Poisonous materials., Technical Name Required.
Incompatibilities
May form explosive mixture with air. Isocyanates are highly flammable and reactive with many compounds, even with themselves. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Reaction with moist air, water or alcohols may form amines and insoluble polyureas and react exothermically, releasing toxic, corrosive or flammable gases, including carbon dioxide; and, at the same time, may generate a violent release of heat increasing the concentration of fumes in the air. Incompatible with amines, aldehydes, alkali metals, ammonia, carboxylic acids, caprolactum, alkaline materials, glycols, ketones, mercaptans, hydrides, organotin catalysts, phenols, strong acids, strong bases, strong reducing agents such as hydrides, urethanes, ureas. Elevated temperatures or contact with acids, bases, tertiary amines, and acylchlorides may cause explosive polymerization. Attacks some plastics, rubber and coatings. Contact with metals may evolve flammable hydrogen gas. May accumulate static electrical charges, and may cause ignition of its vapors. May slowly polymerize if heated above 122F/50C. Contact with metals may evolve flammable hydrogen gas.
Waste Disposal
Methylene bis(4-cyclohexylisocyanate) isdissolved in acetone or any other combustible solvent and burned in a chemicalincinerator equipped with an afterburner andscrubber.
Methylene-bis(4-cyclohexylisocyanate) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20296 | 58 | Inquiry |
| Hebei Kangcang new material Technology Co., LTD | +8615713292910 | China | 341 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9336 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29896 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 13193 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |