2-Methylbenzimidazole
- CAS No.
- 615-15-6
- Chemical Name:
- 2-Methylbenzimidazole
- Synonyms
- 2-METHYL-1H-BENZO[D]IMIDAZOLE;2-methyl-benzimidazol;MethylbenziMidazole;1H-Benzimidazole, 2-methyl-;AKOS 90363;RARECHEM AQ NN 0067;2-METHYLENZIMIDAZOLE;2-METHYLBENZIMIDAZOLE;Methyl-2-benzimidazole;1H-2-Methylbenzimidazol
- CBNumber:
- CB5439553
- Molecular Formula:
- C8H8N2
- Molecular Weight:
- 132.16
- MOL File:
- 615-15-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/8 17:36:13
| Melting point | 175-177 °C (lit.) |
|---|---|
| Boiling point | 234.08°C (rough estimate) |
| Density | 1.1083 (rough estimate) |
| refractive index | 1.6013 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 6.19(at 25℃) |
| color | Light beige to brown |
| Water Solubility | slightly soluble |
| BRN | 112264 |
| InChIKey | LDZYRENCLPUXAX-UHFFFAOYSA-N |
| CAS DataBase Reference | 615-15-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1H-benzimidazole, 2-methyl-(615-15-6) |
| EPA Substance Registry System | 1H-Benzimidazole, 2-methyl- (615-15-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41-20/21/22 | |||||||||
| Safety Statements | 26-39-45-44 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DD9100000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
2-Methylbenzimidazole price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | M29800 | 2-Methylbenzimidazole 98% | 615-15-6 | 5G | ₹2100.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M29800 | 2-Methylbenzimidazole 98% | 615-15-6 | 100G | ₹5239.3 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M0286 | 2-Methylbenzimidazole min. 98.0 % | 615-15-6 | 25G | ₹2500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M0286 | 2-Methylbenzimidazole min. 98.0 % | 615-15-6 | 250G | ₹11300 | 2022-05-26 | Buy |
2-Methylbenzimidazole Chemical Properties,Uses,Production
Chemical Properties
light beige to brown crystalline powder. Soluble in alcohol, ether, hot water and sodium hydroxide solution, insoluble in benzene.
Uses
- 2-Methylbenzimidazole is an important pharmacophore widely used in medicinal chemistry for the synthesis of various antibacterial and antifungal agents.
- It can be used as a key precursor to synthesize substituted benzimidazo[1,2-a]quinolones.
- It can be used in the synthesis of reversible solid-to-liquid phase transition coordination polymer crystals.
- 2-Methylbenzimidazole also exhibits corrosion inhibition.
Preparation
2-Methylbenzimidazole is synthesized by the condensation of o-phenylenediamine with acetic acid. The mixture of o-phenylenediamine and acetic acid is heated at 100°C for 2 hours and then cooled slowly. 10% sodium hydroxide solution is added slowly to the mixture until it is slightly alkaline. The mixture is filtered and washed with cold water. The crude product is then recrystallized with water and decolorized with activated charcoal to obtain the final product. The yield is 68%.
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
2-Methylbenzimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 377)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Shree Ganesh Dye Chem | +91 079-26872726 | Gujarat, India | 97 | 58 | Inquiry |
| Chemox Chemopharma Industries | +91-9909083070 +91-9824151570 | Gujarat, India | 13 | 58 | Inquiry |
| Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| SR FIne Chemicals | 09849728682 | Hyderabad, India | 5 | 58 | Inquiry |
| J R Chemicals | 08048371722Ext 420 | Maharashtra, India | 11 | 58 | Inquiry |
| Arnish Chemicals | 08048372239Ext 470 | Gujarat, India | 5 | 58 | Inquiry |
| PEE ESS AROMATICS | +91 4426247322 | New Delhi, India | 258 | 30 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Shree Ganesh Dye Chem | 58 |
| Chemox Chemopharma Industries | 58 |
| Sri Neelima Laboratories | 58 |
| A.J Chemicals | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| SR FIne Chemicals | 58 |
| J R Chemicals | 58 |
| Arnish Chemicals | 58 |
| PEE ESS AROMATICS | 30 |
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