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ARA-S

ARA-S Structure
CAS No.
187224-29-9
Chemical Name:
ARA-S
Synonyms
ARA-S;N-ARACHIDONOYL L-SERINE;N-[1-OXO-(5Z,8Z,11Z,14Z-EICOSATETRAENYL)]-L-SERINE;L-Serine, N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]-
CBNumber:
CB5470587
Molecular Formula:
C23H37NO4
Molecular Weight:
391.54
MOL File:
187224-29-9.mol
Modify Date:
2023/7/14 17:47:39
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ARA-S Properties

Boiling point 607.6±55.0 °C(Predicted)
Density 1.027±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 2 mg/ml
pka 3.26±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS08
Signal word  Danger
Hazard statements  H225-H350
Precautionary statements  P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
NFPA 704
3
0 0

ARA-S Chemical Properties,Uses,Production

Description

Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature. N-Arachidonoyl-L-serine (ARA-S) is one such recently isolated endocannabinoid with an unusual activity profile. ARA-S does not bind to central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors or vanilloid receptor 1 (VR1). Like cannabidiol, ARA-S (5 mg/kg) antagonizes the hypotensive effects of a 10 mg/kg IV bolus of abnormal cannabidiol (Abn-CBD) in an anesthetized rat blood pressure model. However, similar to Abn-CBD, ARA-S relaxes isolated rat mesenteric arteries and abdominal aorta as well as increases phosphorylation of Akt and mitogen-activated protein kinase (MAPK) in HUVEC. The precise mechanisms of action by ARA-S and Abn-DBD in various vascular preparations appears to be different and requires further investigation.

ARA-S Preparation Products And Raw materials

Raw materials

Preparation Products

ARA-S Suppliers

Global( 29)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Alfa Chemistry United States 24072 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
SHANGHAI ZZBIO CO., LTD. 18019219489 19921389125 China 12064 58 Inquiry
Alfa Chemistry 1-516-6625404 United States 9171 60 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
AXXORA, LLC +41 (0) 61 926 8989 Switzerland 1104 80 Inquiry
United States Biological 1-800-520-3011 United States 6106 58 Inquiry
Shanghai Minmin Biotechnology Co., Ltd. 18021003406 CHINA 6530 58 Inquiry
Supplier Advantage
Alfa Chemistry 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Shanghai Acmec Biochemical Technology Co., Ltd. 58
Aladdin Scientific 58
SHANGHAI ZZBIO CO., LTD. 58
Alfa Chemistry 60
Cayman Chemical Company 81
AXXORA, LLC 80
United States Biological 58
Shanghai Minmin Biotechnology Co., Ltd. 58

187224-29-9(ARA-S)Related Search:

R(+)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE ANANDAMIDE ARA-S NAGLY N-(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)-L-ALANINE
N-ARACHIDONOYL L-SERINE N-[1-OXO-(5Z,8Z,11Z,14Z-EICOSATETRAENYL)]-L-SERINE ARA-S L-Serine, N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]- 187224-29-9 Cannabinoid receptor