ANANDAMIDE
- CAS No.
- 94421-68-8
- Chemical Name:
- ANANDAMIDE
- Synonyms
- AEA;ARACHIDONOYL ETHANOLAMIDE;N-ARACHIDONOYLETHANOLAMINE;ARACHIDONYLETHANOLAMIDE;(5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide;8Z;ANANDAMIDE;14-tetraenamide;ANANDAMIDE AEA?;anandamide(20.4,n-6)
- CBNumber:
- CB7168648
- Molecular Formula:
- C22H37NO2
- Molecular Weight:
- 347.53
- MOL File:
- 94421-68-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/14 17:13:14
| Boiling point | 522.3±50.0 °C(Predicted) |
|---|---|
| Density | 0.92 g/mL at 25 °C (lit.) |
| Flash point | 14 °C |
| storage temp. | -20°C |
| solubility | ethanol: soluble |
| form | oil |
| pka | 14.48±0.10(Predicted) |
| color | light yellow |
| Water Solubility | 413ug/L(25 ºC) |
| Stability | Stable for 1 year from date of purchase as supplied. Subject to oxidation – protect from air. Solutions in degassed DMSO or ethanol may be stored under nitrogen or argon at -80°C for up to 1 month. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Warning |
| Hazard statements | H314 |
| Precautionary statements | P264b-P271-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P403+P233-P501c |
| Hazard Codes | F |
| Risk Statements | 11 |
| Safety Statements | 24/25-16-7 |
| RIDADR | UN 1170 3/PG 2 |
| WGK Germany | 3 |
| RTECS | JX3842500 |
ANANDAMIDE price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A0580 | Arachidonylethanolamide ≥97.0% (TLC), oil | 94421-68-8 | 5MG | ₹11149.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A0580 | Arachidonylethanolamide ≥97.0% (TLC), oil | 94421-68-8 | 25MG | ₹24973.28 | 2022-06-14 | Buy |
ANANDAMIDE Chemical Properties,Uses,Production
Definition
ChEBI: An N-(polyunsaturated fatty acyl)ethanolamine resulting from the formal condensation of carboxy group of arachidonic acid with amino group of ethanolamine.
Hazard
A reproductive hazard.
Biological Activity
Endogenous cannabinoid and vanilloid receptor agonist, in water-soluble emulsion (for details see TocrisolveTM 100). K i values are 89 and 371 nM for CB 1 and CB 2 receptors respectively; EC 50 values are 18, 31 and 27 nM at GPR55, CB 1 and CB 2 respectively; pK i = 5.68 for rVR1. Also blocks TNF- α -induced NF-kB activation via direct inhibition of IKK. Also available as the pure oil dissolved in ethanol (N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide ).
Enzyme inhibitor
This lipid neurotransmitter and endocannabinoid receptor ligand (FW = 347.54 g/mol; CAS 94421-68-8), also known as arachidonylethanolamide, inhibits calcium ion currents and activates the MAP kinase signaling pathway. Anandamide is a naturally occurring effector of central and peripheral nervous systems, as mediated by CB1 and CB2 cannabinoid receptors, respectively. (These receptors were originally characterized as binding Δ9 -tetrahydrocannabinol, or THC, marijuana’s major psychoactive ingredient.) Anandamide, 2-arachidonoylglycerol, and congeners (N- oleoylethanolamide and N-palmitoylethanolamide) are lipophilic signalling molecules with multiple physiological roles in learning and memory, neuroinflammation, oxidative stress, neuroprotection and neurogenesis. Anandamide likewise plays a role in regulating uterine implantation of the early-stage embryo (blastocyst). Anandamide synthesis occurs from N- acetylphosphatidylethanolamine by multiple pathways that include phospholipase A2, phospholipase C, and NAPE-hydrolyzing phospholipase D (or NAPE-PLD). Target(s): adenylate cyclase; Na + channels; a7-nicotinic acetylcholine receptor; 5 HT3 receptors; Ca 2+ channels; K+ channels, voltage-gated; acylglycerol lipase, or monoacylglycerol lipase.
ANANDAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 7034 | 58 | Inquiry |
| Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | China | 3146 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
| Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | China | 1035 | 58 | Inquiry |
| Hebei Linwo New Material Technology Co., LTD | +8618134091113 | China | 991 | 58 | Inquiry |
| Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3582 | 58 | Inquiry |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | China | 2605 | 58 | Inquiry |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
94421-68-8(ANANDAMIDE)Related Search:
1of4
chevron_right