DEA

DEA Structure
CAS No.
150314-35-5
Chemical Name:
DEA
Synonyms
ANANDAMIDE;7,10,13,16-Dtea;DOCOSATETRAENYLETHANOLAMIDE;DOCOSATETRAENOYL ETHANOLAMIDE;7,10,13,16-docosatetraenylethanolamide;7,10,13,16-Docosatetraenoylethanolamine;(all-Z)-N-(7,10,13,16-Docosatetraenoyl)ethanolamine;Anandamide (22:4, n-6) (Docosatetraenylethanolamide);N-(2-HYDROXYETHYL)-7Z, 10Z, 13Z, 16Z-DOCOSATETRAENAMIDE;N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide (all-Z)-
CBNumber:
CB8339388
Molecular Formula:
C24H41NO2
Molecular Weight:
375.59
MOL File:
150314-35-5.mol
Modify Date:
2023/6/8 9:03:09

DEA Properties

Boiling point 544.5±50.0 °C(Predicted)
Density 0.932±0.06 g/cm3(Predicted)
storage temp. Desiccate at -20°C
solubility DMF: 10 mg/ml; DMSO: 30 mg/ml; Ethanol: 100 mg/ml; Ethanol:PBS (1:2): 8 mg/ml; PBS (pH 7.2): <100 μg/ml
pka 14.49±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS08
Signal word  Danger
Hazard statements  H225-H350
Precautionary statements  P201-P202-P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P308+P313-P370+P378-P403+P235-P405-P501
NFPA 704
3
0 0

DEA Chemical Properties,Uses,Production

Description

Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA. However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated.

Uses

(7Z,10Z,13Z,16Z)-N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide is an endocannabinoid and an analog of anandamide, which is an endogenous cannabinoid and TRPV1 receptor agonist.

Biological Activity

Potent endocannabinoid ( anandamide analog) that activates CB 1 receptors in microglia and binds to rat synaptosomal membranes (K I = 34.4 nM). Cannabimimetic in vivo .

DEA Preparation Products And Raw materials

Raw materials

Preparation Products

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7,10,13,16-docosatetraenylethanolamide 7,10,13,16-Docosatetraenamide, N-(2-hydroxyethyl)-, (all-Z)- 7,10,13,16-Dtea DOCOSATETRAENOYL ETHANOLAMIDE DOCOSATETRAENYLETHANOLAMIDE N-(2-HYDROXYETHYL)-7Z, 10Z, 13Z, 16Z-DOCOSATETRAENAMIDE ANANDAMIDE N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide (all-Z)- 7,10,13,16-Docosatetraenoylethanolamine Anandamide (22:4, n-6) (Docosatetraenylethanolamide) (7Z,10Z,13Z,16Z)-N-(2-hydroxyethyl)docosa-7,10,13,16-tetraenamide 7,10,13,16-Docosatetraenamide, N-(2-hydroxyethyl)-, (7Z,10Z,13Z,16Z)- (all-Z)-N-(7,10,13,16-Docosatetraenoyl)ethanolamine 150314-35-5 Cannabinoid receptor