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RITODRINE

RITODRINE Structure
CAS No.
26652-09-5
Chemical Name:
RITODRINE
Synonyms
Lavopa;Premar;RITODRINE;ritodrina;Formoterol-d;RITODRINE USP/EP/BP;Phenoxybenzamine hydrochl;Ritodrine Impurity 2 (Ritodrine);(1R,2S)-2-(4-Hydroxyphenethylamino)-1-(4-hydroxyphenyl)-1-propanol;4-[(1R,2S)-1-Hydroxy-2-[2-(4-hydroxyphenyl)ethylamino]propyl]phenol
CBNumber:
CB5476882
Molecular Formula:
C17H21NO3
Molecular Weight:
287.35
MOL File:
26652-09-5.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:36

RITODRINE Properties

Melting point 88-90 °C
Boiling point 512.3±45.0 °C(Predicted)
Density 1.213±0.06 g/cm3(Predicted)
pka pKa 9.0 (Uncertain)

RITODRINE Chemical Properties,Uses,Production

Description

Ritodrine, 4-hydroxy-α-[1-[(4′-hydroxyphenethyl)amino]ethyl]benzylic alcohol (11.1.19), differs slightly from epinephrine, and in the given example only one hydroxyl group has been added to the aromatic ring of the phenylethylamino region of classic sympathomimetics. The second major difference between the examined series is the replacement of the traditionally terminal iso-propyl or tert-butylamine region with a p-hydroxyphenylethylamine. Finally, the third difference is the presence of a methyl group at the α-atom of the phenylethylamine region of sympathomimetics, which makes it similar to isoetharine.

Uses

Ritodrine is a selective β2-adrenoreceptor stimulant, predominantly of the urino-genital system. It is used as a tocolytic agent for problems associated with premature miscarriages, and only in specialized medical facilities.

General Description

Ritodrine is a selective β2-agonist that wasdeveloped specifically for use as a uterine relaxant. Its uterineinhibitory effects are more sustained than its effects onthe cardiovascular system, which are minimal comparedwith those caused by nonselective β-agonists. The cardiovasculareffects usually associated with its administrationare mild tachycardia and slight diastolic pressure decrease.Usually, it is administered initially by intravenous infusionto stop premature labor and subsequently it may be givenorally.

Clinical Use

Ritodrine is a selective β2-agonist that is used exclusively for relaxing uterine muscle and inhibiting the contractions of premature labor. Terbutaline, in addition to its use as a bronchodilator, also has been used for halting the contractions of premature labor.

RITODRINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 8744 58 Inquiry
Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664 China 3635 55 Inquiry
Jiangsu Zhixinting Technology Co., Ltd 18221391031 China 504 58 Inquiry
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 China 29802 58 Inquiry
Chengdu Saint - Kay Biotechnology Co., Ltd. 028-85157043 15882256948 China 4395 58 Inquiry
Shanghai Aitixi Biotechnology Co., Ltd 18721763493 18721763493 China 991 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9268 58 Inquiry
4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)-benzenemethano( 4-hydroxy-alpha-(1-((2-(4-hydroxyphenyl)ethyl)amino)ethyl)benzenemethanol(r* erythro-p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzylalcohol RITODRINE Benzenemethanol, 4-hydroxy-a-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (aS)-rel- (9CI) Benzenemethanol, 4-hydroxy-a-[1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (R*,S*)- Benzyl alcohol, p-hydroxy-a-[1-[(p-hydroxyphenethyl)amino]ethyl]-, erythro- (8CI) (1R,2S)-1-(4-Hydroxyphenyl)-2-[(4-hydroxyphenethyl)amino]-1-propanol (1R,2S)-2-(4-Hydroxyphenethylamino)-1-(4-hydroxyphenyl)-1-propanol (1R,2S)-2-[(4-Hydroxyphenethyl)amino]-1-(4-hydroxyphenyl)-1-propanol (αR)-4-Hydroxy-α-[(S)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]benzenemethanol (αR)-p-Hydroxy-α-[(S)-1-[(p-hydroxyphenethyl)amino]ethyl]benzyl alcohol Lavopa Premar 4-[(1R,2S)-1-Hydroxy-2-[2-(4-hydroxyphenyl)ethylamino]propyl]phenol p-hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)-benzylalcohoerythr ritodrina Ritodrine Impurity 2 (Ritodrine) RITODRINE USP/EP/BP Benzenemethanol, 4-hydroxy-α-[(1R)-1-[[2-(4-hydroxyphenyl)ethyl]amino]ethyl]-, (αS)-rel- 4-[2-[[(1S,2R)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol Phenoxybenzamine hydrochl Formoterol-d 26652-09-5