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5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one

CAS No.: 885-70-1

Chemical Name:: 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one

Synonyms: 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;LS 75;Pirenzepine EP Impurity B;11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one;5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE;5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one;1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro-

CBNumber:: CB5488339

Molecular Formula:: C12H9N3O

Molecular Weight:: 211.22

MOL File:: 885-70-1.mol

Modify Date:: 2023/4/23 13:52:06

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5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Properties

Melting point	292-293℃
Boiling point	336℃
Density	1.275
Flash point	157℃
storage temp.	Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	11.58±0.20(Predicted)
color	Light Beige to Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Chemical Properties,Uses,Production

Uses

5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, can be used in the synthesis of fluorescent pirenzepine derivatives, used as potential bitopic ligands of the Human M1 Muscarinic receptor.

Synthesis

Synthesis_885-70-1
In a 1000 ml reaction flask,Add 600 ml of butanol,100 g of 2-amino-N- (2-chloropyridyl-3-yl) benzamide,2 ml of concentrated sulfuric acid,The reaction was refluxed for 3 hours at a reaction temperature of 80 ?? C,Cooled to room temperature,filter,Washed with acetone,50-60 ?? C in vacuo to give 98 g of a pale yellow solid product,Yield 98percent, purity 99percent.

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate N-(2-CHLOROPYRIDIN-3-YL)-2-NITROBENZAMIDE 2-Chloro-3-pyridinamine 2-Nitrobenzoyl chloride

Preparation Products

5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Suppliers

Global( 82)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	China	34571	58	Inquiry
WinWin Chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	China	14279	58	Inquiry
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	CHINA	9427	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
Labnetwork lnc.	+86-27-50766799 +8618062016861	China	19994	58	Inquiry

Supplier	Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
WinWin Chemical CO., Limited	58
Baoji Guokang Healthchem co.,ltd	58
Nextpeptide Inc	58
Labnetwork lnc.	58

885-70-1(5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one)Related Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 11-[[4-[4-(DIETHYLAMINO)BUTYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE BIBN 99 5,11-Dihydro-11-chloroacetyl-6H-pyrido[2,3-b][1,4]benzodiazepine-6-one Pirenzepine

AF-DX 384 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-(1H-imidazol -1-ylacetyl)-, hydrate Pirenzepine hydrochloride tripitramine

11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE PIRENZEPINE, [N-METHYL-3H]- AF-DX 384, [2,3-DIPROPYLAMINO-3H]-

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5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE LS 75 11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one 5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one AK-36728 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro- 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro- 1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine Pirenzepine EP Impurity B 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 885-70-1