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N-Ethylmaleimide

N-Ethylmaleimide Structure
CAS No.
128-53-0
Chemical Name:
N-Ethylmaleimide
Synonyms
NEM;1-ETHYL-1H-PYRROLE-2,5-DIONE;N-Ethylmaleinimide;1H-Pyrrole-2,5-dione, 1-ethyl-;NEMI;NSC 7638;N-Ethylm;NEMI/NEM;usafb-121;USAF B-121
CBNumber:
CB5748314
Molecular Formula:
C6H7NO2
Molecular Weight:
125.13
MOL File:
128-53-0.mol
Modify Date:
2023/5/18 11:31:04

N-Ethylmaleimide Properties

Melting point 43-46 °C(lit.)
Boiling point 210 °C(lit.)
Density 1.2500 (rough estimate)
refractive index 1.4430 (estimate)
Flash point 73 °C
storage temp. 2-8°C
solubility methanol: 1 M at 20 °C, clear, colorless
form Crystalline Powder
pka -2.18±0.20(Predicted)
color White to off-white
Water Solubility 1 g/L (20 ºC)
Sensitive Light Sensitive
Merck 14,3822
BRN 112448
Stability Stable. Combustible. Incompatible with strong oxidizing agents. Refrigerate.
InChIKey HDFGOPSGAURCEO-UHFFFAOYSA-N
CAS DataBase Reference 128-53-0(CAS DataBase Reference)
NIST Chemistry Reference 1H-pyrrole-2,5-dione, 1-ethyl-(128-53-0)
EPA Substance Registry System N-Ethylmaleimide (128-53-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H300-H311-H314-H317
Precautionary statements  P260-P280-P301+P310+P330-P303+P361+P353-P305+P351+P338+P310
Hazard Codes  T+
Risk Statements  21-28-34-43-20/21
Safety Statements  26-28-36/37/39-45-28A
RIDADR  UN 2928 6.1/PG 2
WGK Germany  3
RTECS  UX9625000
19
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29251900
NFPA 704
0
3 0

N-Ethylmaleimide price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) E3876 N-Ethylmaleimide crystalline, ≥98% (HPLC) 128-53-0 5G ₹4427.43 2022-06-14 Buy
Sigma-Aldrich(India) E3876 N-Ethylmaleimide crystalline, ≥98% (HPLC) 128-53-0 25G ₹14159.1 2022-06-14 Buy
Sigma-Aldrich(India) E3876 N-Ethylmaleimide crystalline, ≥98% (HPLC) 128-53-0 100G ₹47478.45 2022-06-14 Buy
Sigma-Aldrich(India) E1271 N-Ethylmaleimide BioXtra, ≥98% (HPLC) 128-53-0 1G ₹5109.4 2022-06-14 Buy
Sigma-Aldrich(India) E1271 N-Ethylmaleimide BioXtra, ≥98% (HPLC) 128-53-0 5G ₹10143.03 2022-06-14 Buy
Product number Packaging Price Buy
E3876 5G ₹4427.43 Buy
E3876 25G ₹14159.1 Buy
E3876 100G ₹47478.45 Buy
E1271 1G ₹5109.4 Buy
E1271 5G ₹10143.03 Buy

N-Ethylmaleimide Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+ dependent internucleosomal DNA fragmentation.

Hazard

Lachrymator when liquid, a strong irritant.

Safety Profile

Poison by intraperitoneal route. Human mutation data reported. Vapors are hlghly irritating. When heated to decomposition it emits toxic fumes of NOx.

N-Ethylmaleimide Preparation Products And Raw materials

Global( 295)Suppliers
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Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
usafb-121 N-ETHYLMALEIMIDE 1-Ethyl-1H-pyrrole-2,5-dione~NEM N-ETHYLMALEIMIDE SIGMAULTRA N-ETHYLMALEIMIDE 99+% N-EthylmaleimideA.R. N-Ethylmaleimide-D5 1-ETHYLPYRROLE-2,5-DIONE N-Ethylmaleinimid N-ETHYLMALEIMIDE extrapure 2,5-Dioxo-1-ethyl-3-pyrroline N-ETHYLMALEIMIDERESEARCH GRADE NEMI N-Ethylmaleimide, 98+% N-EthylMaleiMide(NEMI) N-EthylMaleiMide, 99+% 5GR NSC 7638 1-ethyl-1h-pyrrole-5-dione 5-dione,1-ethyl-1H-Pyrrole-2 ethvlmaleimide Ethylmaleimide Maleic acid N-ethylimide maleicacidn-ethylimide Maleimide, N-ethyl- n-ethvlmaleimide n-ethyl-maleimid USAF B-121 N-ETHYLMALEIMIDE BIOULTRA, >= 99.0% N-ETHYLMALEIMIDE BIOXTRA N-Ethylmaleimide≥ 99.5% (GC) N-Ethylmaleimide - CAS 128-53-0 - Calbiochem N-Ethylmaleimide, 99%, reagent grade N-Ethylmaleimide> N-Ethylm N-Ethylmaleimide(NEMI),≥98% N-Ethylmaleimide ISO 9001:2015 REACH n-Ethylmaleimide, ≥99.0% (HPLC) N-Ethylmaleimide ExiPlus, Multi-Compendial, 99% N-ETHYL MALEIMIDE For Synthesis 1-ETHYL-1H-PYRROLE-2,5-DIONE NEM 1H-Pyrrole-2,5-dione, 1-ethyl- N-Ethylmaleinimide N-ETHYLMALEMIDE N-ETHYLMALEIMIDE NEM 1-Ethyl-1H-pyrrole-2,5-dione NEMI/NEM 128-53-0 204-892-4 C6D5H2NO2 N-Substituted Maleimides, Succinimides & Phthalimides N-Substituted Maleimides Life Science Chemical Reagents N-Substituted Maleimides N-Substituted Maleimides, Succinimides & Phthalimides Amines Heterocycles