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N,N'-bis-(2-Chloroethyl)urea

N,N'-bis-(2-Chloroethyl)urea Structure
CAS No.
2214-72-4
Chemical Name:
N,N'-bis-(2-Chloroethyl)urea
Synonyms
BCU;NSC 36198;Carmustine EP Impurity A;Carmustine impurity A CRS;Caprylic Acid Impurity 17;n,n'-bis-(2-chloroethyl)urea;CarMustine Related CoMpound A;Urea, N,N'-bis(2-chloroethyl)-;Carmustine impurity A (C0580010);Carmustine USP Related Compound A
CBNumber:
CB5875119
Molecular Formula:
C5H10Cl2N2O
Molecular Weight:
185.05
MOL File:
2214-72-4.mol
Modify Date:
2023/7/13 17:52:38

N,N'-bis-(2-Chloroethyl)urea Properties

Melting point 128-129 °C
Boiling point 358.2±27.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
pka 12.99±0.46(Predicted)
Stability Hygroscopic, Unstable in Solution
InChIKey VBWBRZHAGLZNST-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2924190002

N,N'-bis-(2-Chloroethyl)urea price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3003 Carmustine Related Compound A pharmaceutical secondary standard, certified reference material 2214-72-4 50MG ₹51635.25 2022-06-14 Buy
Product number Packaging Price Buy
PHR3003 50MG ₹51635.25 Buy

N,N'-bis-(2-Chloroethyl)urea Chemical Properties,Uses,Production

Uses

1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine (C183875), an alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.

N,N'-bis-(2-Chloroethyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 84)Suppliers
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Acura Life Sciences +917780672646 Hyderabad, India 37 58 Inquiry
Scinva Chemicals and Pharmaceuticals Pvt Ltd +91-7406196725 +91-7406196725 Karnataka, India 71 58 Inquiry
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BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Carmustine Related Compound A (10 mg) (1,3-bis(2-chloroethyl)urea) CarMustine Related CoMpound A BCU NSC 36198 3-(diethylamino)-1-(2,4,6-trimethoxyphenyl)-1-propanone Carmustine impurity A CRS Carmustine impurity A (C0580010) Urea, N,N'-bis(2-chloroethyl)- Carmustine EP impurity A/ Carmustine Related Compound A (1,3-Bis(2-chloroethyl)urea) Carmustine EP Impurity A Carmustine Related Compound A (1,3-bis(2-chloroethyl)urea) (1096735) Carmustine USP Related Compound A Caprylic Acid Impurity 17 n,n'-bis-(2-chloroethyl)urea 2214-72-4 Mutagenesis Research Chemicals