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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >N,N'-bis-(2-Chloroethyl)urea

N,N'-bis-(2-Chloroethyl)urea

N,N'-bis-(2-Chloroethyl)urea Structure
  • ₹51635.25
  • Product name: N,N'-bis-(2-Chloroethyl)urea
  • CAS: 2214-72-4
  • MF: C5H10Cl2N2O
  • MW: 185.05
  • EINECS:
  • MDL Number:MFCD00068573
  • Synonyms:Carmustine Related Compound A (10 mg) (1,3-bis(2-chloroethyl)urea);CarMustine Related CoMpound A;BCU;NSC 36198;3-(diethylamino)-1-(2,4,6-trimethoxyphenyl)-1-propanone;Carmustine impurity A CRS;Carmustine impurity A (C0580010);Urea, N,N'-bis(2-chloroethyl)-
1 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3003
  • Product descriptionCarmustine Related Compound A pharmaceutical secondary standard, certified reference material
  • Packaging50MG
  • Price₹51635.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3003 Carmustine Related Compound A pharmaceutical secondary standard, certified reference material 50MG ₹51635.25 2022-06-14 Buy

Properties

Melting point :128-129 °C
Boiling point :358.2±27.0 °C(Predicted)
Density :1.245±0.06 g/cm3(Predicted)
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.99±0.46(Predicted)
Stability :Hygroscopic, Unstable in Solution
InChIKey :VBWBRZHAGLZNST-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine (C183875), an alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.

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