Melperone hydrochloride

CAS No.: 1622-79-3

Chemical Name:: Melperone hydrochloride

Synonyms: Melperone HCl;Melperone-d4 HCl;MELPERONE HYDROCHLORIDE;Methylperone hydrochloride;1(4-Fluorophenol)-4-(4-methyl-1-piperidinyl)-1-butanone;1-[3-(p-fluorobenzoyl)propyl]-4-methylpiperazinium chloride;1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one HCl;1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanonehydrochloride;1-(4-Fluorophenyl)-4-(4-Methylpiperidin-1-yl)butan-1-one hydrochloride;1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-, hydrochloride (1:1)

CBNumber:: CB5900763

Molecular Formula:: C15H22ClFN2O

Molecular Weight:: 300.7993832

MOL File:: 1622-79-3.mol

Modify Date:: 2023/6/8 9:02:44

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Melperone hydrochloride Properties

Melting point	209-211℃
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Light Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H361-H302-H332-H312

Precautionary statements

P201-P202-P281-P308+P313-P405-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501

Toxicity

LD50 in rats, mice (mg/kg): 330, 230 orally; 40, 35 i.v. (Christensen)

NFPA 704

	0
2		0

Melperone hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Melperone hydrochloride is a neuroleptic butyrophenone. Melperone is also an antiarrhythmic agent. Melperone is an effective atypical antipsychotic drug used in the treatment of schizophrenia.

Biological Activity

Atypical neuroleptic; 5-HT 2A /D 2 receptor antagonist (K i values are 120 and 180 nM respectively). Causes an increase in dopamine levels in the medial prefrontal cortex (mPFC) and nucleus accumbens and an increase in ACh in the mPFC. Also binds adrenergic α 1 and α 2 receptors (K i values are 180 and 150 nM respectively).

Safety Profile

Poison by ingestion, subcutaneous, and intravenous routes. Experimental teratogenic effects. A neuroleptic drug used to treat anxiety and confusion. When heated to decomposition it emits very toxic fumes of F-, NOx, and HCl.

Melperone hydrochloride Preparation Products And Raw materials

Raw materials

4-Methylpiperidine

Preparation Products

Melperone hydrochloride Suppliers

Global( 54)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Lifecare Laboratories Pvt. Ltd	+91-4023750123 +91-4023750123	Hyderabad, India	18	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
OCEAN TRADING CORPORATION	+91(22) 24921669	New Delhi, India	6211	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	13484	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30250	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry

Supplier	Advantage
Lifecare Laboratories Pvt. Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
OCEAN TRADING CORPORATION	58
CLEARSYNTH LABS LTD.	58
ATK CHEMICAL COMPANY LIMITED	60
Zhengzhou Alfa Chemical Co.,Ltd	58
Career Henan Chemica Co	58
LEAP CHEM CO., LTD.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58

1622-79-3(Melperone hydrochloride)Related Search:

4-Fluorophenol Pipamperone Haloperidine TRIFLUPERIDOL HCL Cloroperone

Melperone hydrochloride 8-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE HYDROCHLORIDE clofluperol Amiperone 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE

N-(P-ISOTHIOCYANATOPHENETHYL)SPIPERONE HYDROCHLORIDE HALOPERIDOL-D4 HALOPERIDOL, [3H(G)]- Haloperidol N-METHYL-8-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-1-PHENYL-1,3,8-TRIAZASPIRO-[4.5]DECAN-4-ONE HYDROCHLORIDE

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1-[3-(p-fluorobenzoyl)propyl]-4-methylpiperazinium chloride 1(4-Fluorophenol)-4-(4-methyl-1-piperidinyl)-1-butanone 1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanonehydrochloride 1-(4-Fluorophenyl)-4-(4-Methylpiperidin-1-yl)butan-1-one hydrochloride Melperone-d4 HCl Methylperone hydrochloride Melperone HCl MELPERONE HYDROCHLORIDE 1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-, hydrochloride (1:1) 1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one HCl 1622-79-3 C16H22FNOHCl C16H23ClFNO