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4-Fluorophenol

4-Fluorophenol Structure
CAS No.
371-41-5
Chemical Name:
4-Fluorophenol
Synonyms
Fluorophenol;P-FLUOROPHENOL;FPO;p-Fluorohenol;4-Fluorphenol;p-Fluorphenol;4-FLUOROPHENOL;P-flrorophenol;p-fluoro-pheno;4-fluoro-pheno
CBNumber:
CB9672628
Molecular Formula:
C6H5FO
Molecular Weight:
112.1
MOL File:
371-41-5.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43

4-Fluorophenol Properties

Melting point 43-46 °C (lit.)
Boiling point 185 °C (lit.)
Density 1.22
Flash point 155 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 80g/l
form Crystalline Solid
pka 9.89(at 25℃)
color Yellow-beige to pink
PH 5.4 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 50 g/L
BRN 1362752
Stability Stable. Flammable. Incompatible with strong oxidizing agents.
Dissociation constant 0 at 27℃
CAS DataBase Reference 371-41-5(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 4-fluoro-(371-41-5)
EPA Substance Registry System Phenol, 4-fluoro- (371-41-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,C,T,F+
Risk Statements  20/21/22-36/37/38-52/53
Safety Statements  26-37/39-61-36
RIDADR  UN 2928 6.1/PG 2
WGK Germany  1
RTECS  SL4550000
10-23
Hazard Note  Corrosive/Harmful
TSCA  T
HazardClass  6.1
PackingGroup  III
HS Code  29081000
NFPA 704
2
2 0

4-Fluorophenol price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F13207 4-Fluorophenol 99% 371-41-5 25G ₹2478.93 2022-06-14 Buy
Sigma-Aldrich(India) F13207 4-Fluorophenol 99% 371-41-5 100G ₹6473.35 2022-06-14 Buy
ALFA India ALF-A11945-36 4-Fluorophenol, 99% 371-41-5 500g ₹21411 2022-05-26 Buy
ALFA India ALF-A11945-22 4-Fluorophenol, 99% 371-41-5 100g ₹6026 2022-05-26 Buy
ALFA India ALF-A11945-14 4-Fluorophenol, 99% 371-41-5 25g ₹2897 2022-05-26 Buy
Product number Packaging Price Buy
F13207 25G ₹2478.93 Buy
F13207 100G ₹6473.35 Buy
ALF-A11945-36 500g ₹21411 Buy
ALF-A11945-22 100g ₹6026 Buy
ALF-A11945-14 25g ₹2897 Buy

4-Fluorophenol Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-Fluorophenol is a fluorinated phenolic compound with various applications as a starting reagent for synthesizing pharmaceuticals. It is a widely used intermediate in the industrial production of several drugs, including cisapride and Sabeluzole by Janssen, Sorbinil by Pfizer, and Progabide by Synthelabo.

Preparation

Acetyl hypofluorite also will fluoro-demetallate benzene derivatives, for example mercury derivatives of phenol gave 4-fluorophenol.
synthesis of 4-Fluorophenol

Definition

ChEBI: 4-fluorophenol is a fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine. It is a fluorophenol and a member of monofluorobenzenes. It is used as an intermediate in the production of liquid crystals.

Hazard

Irritant.

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