terofenamate

terofenamate Structure
CAS No.
29098-15-5
Chemical Name:
terofenamate
Synonyms
Etoclofene;terofenamate;ethoxymethyl N-(2,6-dichloro-m-tolyl)-anthranilate;2-[(2,6-Dichloro-m-tolyl)amino]benzoic acid ethoxymethyl ester;2-(2,6-Dichloro-3-methylphenyl)aminobenzoic acid ethoxymethyl ester;2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid ethoxymethyl ester
CBNumber:
CB5940947
Molecular Formula:
C17H17Cl2NO3
Molecular Weight:
0
MOL File:
29098-15-5.mol
Modify Date:
2022/12/21 16:56:50

terofenamate Properties

Melting point 73-74°
Density 1.3318 (rough estimate)
refractive index 1.6140 (estimate)

SAFETY

Risk and Safety Statements

Toxicity LD50 in mice, rats (mg/kg): 918, 307 orally; 300, 274 i.p. (Chieli)

terofenamate Chemical Properties,Uses,Production

Originator

Etofen Ilfi,Lusofarmaco,Italy,1980

Manufacturing Process

10 g sodium salt of N-2,6-dichloro-m-tolylanthranilic acid, 3 ml chloromethyl ethyl ether and 80 ml dry acetone were refluxed for 12 hours on waterbath under stirring. The solid was filtered off, and the solution evaporated to dryness. The residue was dissolved in chloroform, washed with sodium carbonate solution, then with water until neutral. After drying on sodium sulfate, the solution was evaporated to dryness. The obtained product was recrystallized from 95% ethanol. Melting point 73°C to 74°C.

Therapeutic Function

Antiinflammatory, Analgesic

terofenamate Preparation Products And Raw materials

Raw materials

Preparation Products

terofenamate Suppliers

Global( 4)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Portail Substances Chimiques 10 20 0000 France 6027 58 Inquiry
Shaanxi Dideu Newmaterial Co., Ltd. 029-63373950 15353716720 China 10011 58 Inquiry
2-(2,6-Dichloro-3-methylphenyl)aminobenzoic acid ethoxymethyl ester 2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid ethoxymethyl ester 2-[(2,6-Dichloro-m-tolyl)amino]benzoic acid ethoxymethyl ester Etoclofene terofenamate ethoxymethyl N-(2,6-dichloro-m-tolyl)-anthranilate 29098-15-5