ChemicalBook > Product Catalog >API >Digestive system drugs >Appetite suppressants and other diet pills >(+)-FENFLURAMINE HYDROCHLORIDE

(+)-FENFLURAMINE HYDROCHLORIDE

(+)-FENFLURAMINE HYDROCHLORIDE Structure
CAS No.
3239-44-9
Chemical Name:
(+)-FENFLURAMINE HYDROCHLORIDE
Synonyms
redux;adifax;d-fenfluramine;DEXFENFLURAMINE;(s)-fenfluramine;(s)-phenethylamin;dextrofenfluramine;DEXFENFLURAMINE HCL;(s)-(+)-fenfluramine;(s)-benzeneethanamin
CBNumber:
CB6149293
Molecular Formula:
C12H16F3N
Molecular Weight:
231.26
MOL File:
3239-44-9.mol
Modify Date:
2022/12/21 16:56:50

(+)-FENFLURAMINE HYDROCHLORIDE Properties

alpha D25 +9.5° (c = 8 in ethanol)
Boiling point 108-112 °C(Press: 12 Torr)
Density 1.078±0.06 g/cm3(Predicted)
pka 10.23±0.19(Predicted)

SAFETY

Risk and Safety Statements

Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  22-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  SH6824000
Toxicity LD50 orally in rats: 114.6 mg/kg (Le Douarec)

(+)-FENFLURAMINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Appetite suppressant (systemic).

Definition

ChEBI: The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.

(+)-FENFLURAMINE HYDROCHLORIDE Preparation Products And Raw materials

FENFLURAMINEHCL(DEXTRO-) (S)-N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine [S,(+)]-N-Ethyl-α-methyl-m-(trifluoromethyl)phenethylamine ethyl-[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amine (+)-FENFLURAMINE HYDROCHLORIDE--DEA*SCHE DULE IV ITE d-n-ethyl-alpha-methyl-m-trifluoromethylphenethylamine redux (+)-fenfluramine hydrochloride--dea*schedule iv I DEXFENFLURAMINE DEXFENFLURAMINE HCL (+)-N-ETHYL-ALPHA-METHYL-M-[TRIFLUOROMETHYL]PHENETHYLAMINE HYDROCHLORIDE (s)-(+)-fenfluramine (s)-benzeneethanamin (s)-fenfluramine (s)-phenethylamin adifax dextrofenfluramine d-fenfluramine Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-, (αS)- (+)-FENFLURAMINE HYDROCHLORIDE USP/EP/BP DBGIVFWFUFKIQN-VIFPVBQESA-N 3239-44-9