ELOCALCITOL

CAS No.: 199798-84-0

Chemical Name:: ELOCALCITOL

Synonyms: BXL 628;Ro 26-9228;ELOCALCITOL;Ellocalciferol;(1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol;Cyclohexanol, 3-[(2E)-2-[(3aS,7aS)-1-[(1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-hepten-1-yl]-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylene-, (1R,3Z,5S)-

CBNumber:: CB61509111

Molecular Formula:: C29H43FO2

Molecular Weight:: 442.65

MOL File:: 199798-84-0.mol

Modify Date:: 2024/7/2 8:55:13

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ELOCALCITOL Properties

Boiling point	568.3±50.0 °C(Predicted)
Density	1.05±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM)
form	A crystalline solid
pka	14.04±0.40(Predicted)
color	White to off-white

ELOCALCITOL Chemical Properties,Uses,Production

Description

BXL-628 is an analog of vitamin D₃ that has diverse biological activities. It increases death of androgen-stimulated human benign prostatic hyperplasia (BPH) cells via induction of apoptosis in a dose-dependent manner. In vivo, BXL-628 completely inhibits androgen-stimulated prostate overgrowth in a rat model of BPH. It reduces expression of IL-13 and IgE/mast cell-derived protease 1 (MMCP1) and decreases edema and leukocyte infiltration in the bladder wall in a mouse model of allergen-induced interstitial cystitis. BXL-628 also reduces the number of adherent endometrial stromal cells and decreases the total weight of endometrial lesions in a mouse model of endometriosis. Formulations containing BXL-628 are under clinical investigation for the treatment of BPH.

ELOCALCITOL Preparation Products And Raw materials

Raw materials

Preparation Products

ELOCALCITOL Suppliers

Global( 41)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	China	52861	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	China	25363	58	Inquiry
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	China	9991	58	Inquiry
PT CHEM GROUP LIMITED	+86-85511178 +86-85511178	China	35426	58	Inquiry
GIHI CHEMICALS CO.,LIMITED	+8618058761490	China	49999	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	23963	58	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6618	81	Inquiry

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Coresyn Pharmatech Co., Ltd.	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
TargetMol Chemicals Inc.	58
Cayman Chemical Company	81

199798-84-0(ELOCALCITOL)Related Search:

Paricalcitol ELOCALCITOL 2,6-DIMETHYL-3,7-OCTADIEN-2-OL

ELOCALCITOL BXL 628 (1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol Ellocalciferol Cyclohexanol, 3-[(2E)-2-[(3aS,7aS)-1-[(1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-hepten-1-yl]-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylene-, (1R,3Z,5S)- Ro 26-9228 199798-84-0 C29H43FO2