ELOCALCITOL
- CAS No.
- 199798-84-0
- Chemical Name:
- ELOCALCITOL
- Synonyms
- BXL 628;Ro 26-9228;ELOCALCITOL;Ellocalciferol;(1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol;Cyclohexanol, 3-[(2E)-2-[(3aS,7aS)-1-[(1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-hepten-1-yl]-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylene-, (1R,3Z,5S)-
- CBNumber:
- CB61509111
- Molecular Formula:
- C29H43FO2
- Molecular Weight:
- 442.65
- MOL File:
- 199798-84-0.mol
- Modify Date:
- 2025/4/18 9:51:20
| Boiling point | 568.3±50.0 °C(Predicted) |
|---|---|
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM) |
| form | A crystalline solid |
| pka | 14.04±0.40(Predicted) |
| color | White to off-white |
| optical activity | [α]/D +97 to +107°, c =c=1 in methanol |
ELOCALCITOL Chemical Properties,Uses,Production
Description
BXL-628 is an analog of vitamin D3 that has diverse biological activities. It increases death of androgen-stimulated human benign prostatic hyperplasia (BPH) cells via induction of apoptosis in a dose-dependent manner. In vivo, BXL-628 completely inhibits androgen-stimulated prostate overgrowth in a rat model of BPH. It reduces expression of IL-13 and IgE/mast cell-derived protease 1 (MMCP1) and decreases edema and leukocyte infiltration in the bladder wall in a mouse model of allergen-induced interstitial cystitis. BXL-628 also reduces the number of adherent endometrial stromal cells and decreases the total weight of endometrial lesions in a mouse model of endometriosis. Formulations containing BXL-628 are under clinical investigation for the treatment of BPH.
ELOCALCITOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29730 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32222 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | China | 52849 | 58 | Inquiry |
| CR Corporation Limited | +8613062833949 | China | 8647 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | China | 25356 | 58 | Inquiry |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | China | 9984 | 58 | Inquiry |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178; | China | 35425 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49984 | 58 | Inquiry |
| Cayman Chemical Company | (800) 364-9897 | United States | 6213 | 81 | Inquiry |