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4-Chlorobenzhydrol

4-Chlorobenzhydrol Structure
CAS No.
119-56-2
Chemical Name:
4-Chlorobenzhydrol
Synonyms
Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
CBNumber:
CB6151432
Molecular Formula:
C13H11ClO
Molecular Weight:
218.68
MOL File:
119-56-2.mol
Modify Date:
2023/11/17 16:09:38

4-Chlorobenzhydrol Properties

Melting point 58-60 °C (lit.)
Boiling point 150-151°C 2,6mm
Density 1.1178 (rough estimate)
refractive index 1.5260 (estimate)
Flash point 150-151°C/2.6mm
storage temp. 2-8°C
solubility insoluble
pka 13.34±0.20(Predicted)
color White to Off-White
Water Solubility insoluble
BRN 2050235
CAS DataBase Reference 119-56-2(CAS DataBase Reference)
NIST Chemistry Reference Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2)
EPA Substance Registry System Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
TSCA  Yes
HS Code  29062990
NFPA 704
0
1 0

4-Chlorobenzhydrol price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3034 Meclizine Related Compound A pharmaceutical secondary standard, certified reference material 119-56-2 30MG ₹41199.95 2022-06-14 Buy
Sigma-Aldrich(India) 124982 4-Chlorobenzhydrol 98% 119-56-2 1G ₹1800 2022-06-14 Buy
TCI Chemicals (India) C0989 4-Chlorobenzhydrol min. 98.0 % 119-56-2 25G ₹3900 2022-05-26 Buy
TCI Chemicals (India) C0989 4-Chlorobenzhydrol min. 98.0 % 119-56-2 500G ₹19100 2022-05-26 Buy
SRL 91019 4-Chlorobenzhydrol pure, 98% 119-56-2 50Gms ₹3680 2022-05-26 Buy
Product number Packaging Price Buy
PHR3034 30MG ₹41199.95 Buy
124982 1G ₹1800 Buy
C0989 25G ₹3900 Buy
C0989 500G ₹19100 Buy
91019 50Gms ₹3680 Buy

4-Chlorobenzhydrol Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .

Preparation

Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).

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(4-Chlorophenyl)phenylmethanol 4-chloro-alpha-phenyl-benzenemethano 4-Chlorobenzohydrol Benzhydrol, 4-chloro- Benzhydrol, p-chloro- AURORA KA-7061 P-CHLORO BENZHYDROL 4-CHLOROPHENYL PHENYL CARBINOL 4-CHLORO-ALPHA-PHENYL-BENZENEMETHANOL 4-CHLORO-(ALPHA-PHENYL) BENZYL ALCOHOL 4-CHLOROBENZHYDROL 4-Chlorobenzhydryl alcohol 4-CHLORO-O-PHENYLBENZYL ALCOHOL 4-CHLORODIPHENYLCARBINOL 4-CHLORODIPHENYLMETHANOL Benzenemethanol, 4-chloro-.alpha.-phenyl- 4-Chlorodiphenylmethanol~4-Chlororphenyl phenyl carbinol 4-CHLOROBENZHYDROL 98+% 4-Chloro-a-phenyl-benzenemethanol 4-CHLOROBENZHYDROL pure 4-Chloro-α-phenylbenzenemethanol (p-Chlorophenyl)phenylmethanol p-Chlorobenzohydrol Phenyl(4-chlorophenyl)methanol Meclizine Related Compound A (15 mg) (4-chlorobenzhydrol) 4-CHLOROBENZHYDROL FOR SYNTHESIS Buclizine HCl IMpurity-B(BP/EP) Levocetrizine IMpurity 4-Chloro Benzhydrol (Meclozine EP IMpurity B) Meclozine EP IMpurity B (4-Chlorobenzhydrol) BenzeneMethanol, 4-chloro-α-phenyl- Meclozine impurity B Cetirizine 4-Chlorobenzhydrol Impurity (USP) Meclizine USP RC A 4-Chlorobenzhydrol 98% Buclizine EP Impurity B (R)-(4-chlorophenyl)-phenylmethanol Cetirizine Impurity L Meclizine USP Related Compound A Cetirizine Impurity I 4-Chlorobenzhydrol > Meclozine impurity B CRS N-Methyl-2-(pyridin-2-yl)-N-[2-(pyr Levocloperastine CBZ Racemate Meclizine EP Impurity B Meclozine EP Impurity B Meclozine imp-B/4-Chlorobenzhydrol Cetirizine 4-Chlorobenzhydrol Impurity (Meclizine Related Compound A) Meclizine Related Compound A (Cetirizine 4-Chlorobenzhydrol Impurity) Cetrizine 4-chlorobenzyhydrol Impurity Cetirizine Impurity93 4-ChlorobenzhydrolQ: What is 4-Chlorobenzhydrol Q: What is the CAS Number of 4-Chlorobenzhydrol Q: What is the storage condition of 4-Chlorobenzhydrol Q: What are the applications of 4-Chlorobenzhydrol Chlorobenzhydrol Cetirizine 4-Chlorobenzhydrol Impurity Meclozine Dihydrochloride Impurity B Meclozine EP Impurity B (Meclizine USP Related Compound A, 4-Chlorobenzhydrol) Cinnarizine Impurity 12 Meclozine Dihydrochloride EP Impurity B