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ISOCORYDINE HYDROCHLORIDE

ISOCORYDINE HYDROCHLORIDE Structure
CAS No.
475-67-2
Chemical Name:
ISOCORYDINE HYDROCHLORIDE
Synonyms
luteanin;LUTEANINE;artabotrin;Aids138466;Uzokoridin;Isocorydine;Aids-138466;d-isocorydine;l-(+)-isocorydine;S-ISOCORYDINE (+)
CBNumber:
CB6238999
Molecular Formula:
C20H23NO4
Molecular Weight:
341.4
MOL File:
475-67-2.mol
Modify Date:
2023/9/4 16:42:00
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ISOCORYDINE HYDROCHLORIDE Properties

Melting point 216-220 °C(lit.)
alpha D20 +195° (chloroform)
Boiling point 477.03°C (rough estimate)
Density 1.2064 (rough estimate)
refractive index 1.5614 (estimate)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Cryst.
pka 9.41±0.20(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  CE1057950
Toxicity LD50 intraperitoneal in mouse: 104mg/kg

ISOCORYDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Isocorydine is an aporphine alkaloid that has been found in A. squamosa that has vasodilatory and anticancer activities. It reduces the action potential duration and increases the effective refractory period in isolated canine Purkinje fibers when used at a concentration of 30 μM. Isocorydine induces relaxation of norepinephrine-precontracted isolated rabbit aortic strips with an EC50 value of 12.6 μM. It is cytotoxic to A549 lung cancer cells (IC50 = 197.7 μM), as well as Huh7, HepG2, SNU-449, and SNU-387 hepatic cancer cells (IC50s = 161.3, 148, 262.2, and 254.1 μg/ml, respectively). Isocorydine, in combination with doxorubicin, reduces tumor growth in a Huh7 mouse xenograft model.

Uses

sedative, cholinergic

References

See Isocorydine

ISOCORYDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-MENISPERINE IODIDE

ISOCORYDINE HYDROCHLORIDE Suppliers

Global( 149)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Chengdu Greenpure Biopharma CO.,Ltd 18283602253; +8618283602253 China 952 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 990 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Supplier Advantage
Chengdu Greenpure Biopharma CO.,Ltd 58
Chengdu GLP biotechnology Co Ltd 58
Chengdu Biopurify Phytochemicals Ltd. 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Hubei Ipure Biology Co., Ltd 58
ANHUI WITOP BIOTECH CO., LTD 58
Dideu Industries Group Limited 58
Sinoway Industrial co., ltd. 58
Dayang Chem (Hangzhou) Co.,Ltd. 58

ISOCORYDINE HYDROCHLORIDE Spectrum

ISOCORYDINE HYDROCHLORIDE(475-67-2)1HNMR

475-67-2(ISOCORYDINE HYDROCHLORIDE)Related Search:

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LUTEANINE LUTEANINE HYDROCHLORIDE 1,2,10-trimethoxy-6a-alpha-aporphin-11-o 4h-dibenzo(de,g)quinolin-11-ol,5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methy artabotrin d-isocorydine l-(+)-isocorydine luteanin luteanine(aporphine) D-ISOCORYDINE HYDROCHLORIDE (+)-ISOCORYDINE HCL ISOCORYDINE HCL, (+)- (+)-ISOCORYDINE HYDROCHLORIDE ISOCORYDINE HYDROCHLORIDE (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE 11-HYDROXY-1,2,10-TRIMETHOXYAPORPHINE HYDROCHLORIDE (6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-11-ol Isocorydine S-ISOCORYDINE (+) 1,2,10-Trimethoxy-6-methyl-5,6,6A,7-tetrahydro-4H-dibenzo[de,G]quinolin-11-ol Aids138466 Aids-138466 Aporphin-11-ol, 1,2,10-trimethoxy- (+)-isocorynoline (+)-Isocorynoline hydrochloride Uzokoridin 4H-Dibenzo[de,g]quinolin-11-ol, 5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6aS)- Artabotrin|||S-Isocorydine(+)|||Luteanin|||Uzokoridin|||(+)-Isocorynoline 475-67-2 Analytical Chromatography Product Catalog Analytical Standards Asymmetric Synthesis Chiral Building Blocks Others Drug Standards Chromatography Forensic and Veterinary Standards Heterocyclic Building Blocks Inhibitors Miscellaneous Natural Products Alkaloids