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ARRY-380

CAS No.: 937265-83-3

Chemical Name:: ARRY-380

Synonyms: CS-523;Arry-830;ARRY-380;ARRY-380-d3;Arry-380, >=98%;HER2-Inhibitor-1;ARRY380; ARRY 380;ARRY-380 (analog );ARRY-380 USP/EP/BP;ARRY-380;ARRY380; ARRY 380

CBNumber:: CB62554080

Molecular Formula:: C29H27N7O4S

Molecular Weight:: 569.63

MOL File:: 937265-83-3.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:13

Request For Quotation

ARRY-380 Properties

Density	1.43
storage temp.	Store at -20°C
solubility	≥28.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form	solid
pka	6.34±0.19(Predicted)
color	Light brown to brown

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P305+P351+P338

NFPA 704

	0
2		0

ARRY-380 Chemical Properties,Uses,Production

Description

Arry-380 analog was designed as an inhibitor of EGFR (ErbB1).

Uses

ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM and also inhibits EGFR with IC50 of 4 μM.

ARRY-380 Preparation Products And Raw materials

Raw materials

Preparation Products

ARRY-380 Suppliers

Global( 86)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	25247	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810	China	3750	55	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Nanjing Sunlida Biological Technology Co., Ltd.	55

ARRY-380 Spectrum

ARRY-380(937265-83-3)¹HNMR

937265-83-3(ARRY-380)Related Search:

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PLX4032

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ARRY-380 (analog ) Arry-830 ARRY-380;ARRY380; ARRY 380 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a] Arry-380, >=98% ARRY-380 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine HER2-Inhibitor-1 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine ARRY 380 ARRY-380-d3 N-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-Methylphenyl)-6-(5-(((2-(Methylsulfonyl)ethyl)aMino)Methyl)furan-2-yl)quinazolin-4-aMine CS-523 ARRY380; ARRY 380 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine 4-Quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- ARRY-380 USP/EP/BP 937265-83-3 C29H27N7O4S Inhibitors Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds