ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >Akt inhibitors >PHT-427
PHT-427
- CAS No.
- 1191951-57-1
- Chemical Name:
- PHT-427
- Synonyms
- CS-303;PHT-427;CS-0223;PHT-427, >=98%;PHT-427;PHT 427;PHT-427 USP/EP/BP;PHT-427 (CS-0223);PHT-427 Akt Inhibitor XIV PHT427;Akt Inhibitor XIV - CAS 1191951-57-1 - Calbiochem;4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
- CBNumber:
- CB62561491
- Molecular Formula:
- C20H31N3O2S2
- Molecular Weight:
- 409.61
- MOL File:
- 1191951-57-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/10 16:48:32
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
PHT-427 price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 124032 | Akt Inhibitor XIV - CAS 1191951-57-1 - Calbiochem The Akt Inhibitor XIV, also referenced under CAS 1191951-57-1, controls the biological activity of Akt. This small molecule/inhibitor is primarily use | 1191951-57-1 | 10MG | ₹13100 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| 124032 | 10MG | ₹13100 | Buy |
PHT-427 Chemical Properties,Uses,Production
Uses
PHT-427 is a dual Akt and PDPK1 inhibitor with Ki of 2.7 μM and 5.2 μM, respectively.
Enzyme inhibitor
This orally bioavailable, dual Akt/PDPK1 inhibitor (F.Wt. = 409.61; CAS 1191951-57-1 and 1178893-77-0; Solubility (25°C): 80 mg/mL DMSO, <1 mg/mL Water), known systematically as 4-dodecyl-N-(1,3,4-thiadiazol-2- yl)benzenesulfonamide, targets Akt (also known as Protein Kinase B, or PKB) and 3-phosphoinositide-dependent protein kinase-1, with Ki of 2.7 μM and 5.2 μM, respectively. PHT-427 was designed to bind to the pleckstrin homology (PH) auto-inhibitory domains of the signal cascade protein kinase Akt.
PHT-427 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 124)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | China | 11027 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| changzhou huayang technology co., ltd | +8615250961469 | China | 9821 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
1191951-57-1(PHT-427)Related Search:
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PHT-427
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
CS-0223
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide PHT 427
PHT-427
4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide
PHT-427;PHT 427
PHT-427, >=98%
PHT-427 (CS-0223)
PHT-427 USP/EP/BP
Benzenesulfonamide, 4-dodecyl-N-1,3,4-thiadiazol-2-yl-
Akt Inhibitor XIV - CAS 1191951-57-1 - Calbiochem
CS-303
PHT-427 Akt Inhibitor XIV PHT427
1191951-57-1
C20H31N3O2S2
PI3K/Akt/mTOR
Akt
mTOR
PI3K
Inhibitors