Proflavine hemisulfate

- CAS No.
- 1811-28-5
- Chemical Name:
- Proflavine hemisulfate
- Synonyms
- PROFLAVINE HEMISULPHATE;PROFLAVINE HEMISULFATE SALT;3,6-DIAMINOACRIDINIUM MONOHYDROGEN SULFATE;PROFLAVINE SULFATE;PROFLAVINE HEMISULFATE;Proflavin hemisulphate;PROFLAVINE HEMISULFATE;bis(acridine-3,6-diamine);3,6-DIAMINOACRIDINE SULFATE;2 8-DIAMINOACRIDINE SULFATE
- CBNumber:
- CB6285832
- Molecular Formula:
- C13H13N3O4S
- Molecular Weight:
- 307.32
- MOL File:
- 1811-28-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
---|---|
solubility | DMSO (Slightly, Heated), Water (Slightly, Heated) |
form | powder |
color | Orange to Amber to Dark red |
PH | pH (1g/l, 25℃) : 4.0~8.0 |
Water Solubility | H2O: 10mg/mL |
BRN | 3921806 |
Stability | Hygroscopic |
EPA Substance Registry System | 3,6-Acridinediamine, sulfate (2:1) (1811-28-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | AR9065100 | |||||||||
F | 3-8-10-23 | |||||||||
HS Code | 2918.19.9000 | |||||||||
Toxicity | mouse,LD50,subcutaneous,200mg/kg (200mg/kg),Quarterly Journal of Pharmacy & Pharmacology. Vol. 10, Pg. 649, 1937. | |||||||||
NFPA 704 |
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Proflavine hemisulfate price More Price(7)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | P2508 | Proflavine hemisulfate salt hydrate powder | 1811-28-5 | 1G | ₹1872.73 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P2508 | Proflavine hemisulfate salt hydrate powder | 1811-28-5 | 10G | ₹6928 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P2508 | Proflavine hemisulfate salt hydrate powder | 1811-28-5 | 25G | ₹12481.23 | 2022-06-14 | Buy |
TCI Chemicals (India) | D0073 | Proflavine Hemisulfate | 1811-28-5 | 5G | ₹2300 | 2022-05-26 | Buy |
TCI Chemicals (India) | D0073 | Proflavine Hemisulfate | 1811-28-5 | 25G | ₹6700 | 2022-05-26 | Buy |
Proflavine hemisulfate Chemical Properties,Uses,Production
Description
Proflavine Hemisulfate, the hemisulfate form of proflavin, is an acridine-derived fluorescent contrast agent and disinfectant used for cell imaging and antiseptic purposes. Following topical application, proflavin diffuses into cells and intercalates into DNA, leading to its accumulation in and staining of the nucleus. This allows visualization of the nucleus during fluorescence imaging. Such capability enables nuclear morphometry and facilitates the identification of cancer cells. Additionally, proflavin sulfate exerts antimicrobial effects through binding to bacterial DNA, which disrupts DNA synthesis and inhibits bacterial cell growth.
Chemical Properties
orange to brown crystalline powder
Uses
Proflavine Hemisulfate is used in preparation of Adenine and Adenine nucleotides via photochemical demethylation of methyladenines.
Purification Methods
An aqueous solution, after treatment with charcoal, is concentrated, chilled overnight, filtered and the precipitate is rinsed with a little diethyl ether. The precipitate is dried in air, then overnight in a vacuum oven at 70o. [Beilstein 22 I 650, 22/11 V 323.]
Proflavine hemisulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Macsen Labs | +91-7296866111 +91-9309241616 | Rajasthan, India | 11 | 58 | Inquiry |
Innovative Synthetic Molecules | +91 40-24111684 | Hyderabad, India | 526 | 58 | Inquiry |
Loba Chemie Pvt Ltd | +91-22-6663 6663 | Mumbai, India | 498 | 58 | Inquiry |
Macsen Laboratories (Macsen Drugs) | 91-294-2421277 | Rajasthan, India | 16 | 58 | Inquiry |
Ankur Chemicals | +91 294-2482546 | Rajasthan, India | 5 | 58 | Inquiry |
ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1679 | 43 | Inquiry |
Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1994 | 38 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Macsen Labs | 58 |
Innovative Synthetic Molecules | 58 |
Loba Chemie Pvt Ltd | 58 |
Macsen Laboratories (Macsen Drugs) | 58 |
Ankur Chemicals | 58 |
ALPHA CHEMIKA | 43 |
Scientific OEM | 38 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Otto Chemie Pvt. Ltd. | 58 |