Z-LEU-LEU-GLU-AMC

CAS No.: 348086-66-8

Chemical Name:: Z-LEU-LEU-GLU-AMC

Synonyms: Z-ILE-AMC;Z-LLE-AMC;Z-LLG-AMC;Z-LEU-LEU-GLU-MCA;Z-LEU-LEU-GLU-AMC;Z-LEU-LEU-GLY-AMC;CBZ-LEU-LEU-GLU-AMC;Proteasome Substrate II;Cbz-Leu-Leu-Glu-AMC, Z-LLE-AMC;PROTEASOME SUBSTRATE II (FLUOROGENIC)

CBNumber:: CB6298942

Molecular Formula:: C35H44N4O9

Molecular Weight:: 664.75

MOL File:: 348086-66-8.mol

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

Z-LEU-LEU-GLU-AMC Properties

Boiling point	967.8±65.0 °C(Predicted)
Density	1.253±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO: soluble
form	solid
pka	4.43±0.10(Predicted)
color	Solid lyophilized powder

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

Z-LEU-LEU-GLU-AMC price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C0483	Z-Leu-Leu-Glu-7-amido-4-methylcoumarin ≥95%, solid	348086-66-8	5MG	₹41448.93	2022-06-14	Buy

Product number	Packaging	Price	Buy
C0483	5MG	₹41448.93	Buy

Z-LEU-LEU-GLU-AMC Chemical Properties,Uses,Production

Description

Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC is typically used in cell lysates after experimental treatment.

Uses

A fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (caspase-like) activity of the proteasome which may be stimulated in the presence of Mg2+ ions and rapidly inactivated by N-acetylimidazole

General Description

Z-Leu-Leu-Glu-7-amido-4-methylcoumarin is a fluoropeptide. It acts as a substrate for caspase-like activity.

Z-LEU-LEU-GLU-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

Z-LEU-LEU-GLU-AMC Suppliers

Global( 86)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	China	2345	58	Inquiry
Nanjing TGpeptide	+86-13347807150 +86-13347807150	China	3279	58	Inquiry
Zhejiang Hangyu API Co., Ltd	+8617531972939	China	2944	58	Inquiry
DONBOO AMINO ACID COMPANY	+8613063595538	China	9365	58	Inquiry
Sigma-Aldrich	021-61415566 800-8193336	China	51471	80	Inquiry

Supplier	Advantage
A.J Chemicals	58
Career Henan Chemica Co	58
BOC Sciences	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nextpeptide Inc	58
Chengdu Youngshe Chemical Co., Ltd.	58
Nanjing TGpeptide	58
Zhejiang Hangyu API Co., Ltd	58
DONBOO AMINO ACID COMPANY	58
Sigma-Aldrich	80

348086-66-8(Z-LEU-LEU-GLU-AMC)Related Search:

Z-LEU-LEU-ARG-AMC Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN Z-LEU-LEU-OH Z-LLL-AMC BENZYLOXYCARBONYL-L-LEUCYL-L-ARGINYLGLYCYLGLYCINE 4-METHYLCOUMARYL-7-AMIDE

H-GLU(AMC)-OH MG-115 Z-LEU-LEU-GLU-AMC Z-LEU-LEU-GLU-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN GLUTAMIC ACID(ANILIDE)-OH

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CBZ-LEU-LEU-GLU-AMC CARBOBENZOXY-L-LEUCYL-L-LEUCYL-L-GLUTAMIC-ACID-ALPHA-(4-METHYLCOUMARINYL)-7-AMIDE BENZYLOXYCARBONYL-L-LEUCYL-L-LEUCYL-L-GLUTAMIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE) PROTEASOME SUBSTRATE II (FLUOROGENIC) Z-LEU-LEU-GLU-7-AMIDO-4-METHYLCOUMARIN Z-LEU-LEU-GLU-7-AMINO-4-METHYLCOUMARIN Z-LEU-LEU-GLU-AMC Z-LEU-LEU-GLU-MCA Z-LLE-AMC Z-ILE-AMC N-[(Phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alpha-glutamine Z-LLG-AMC Cbz-Leu-Leu-Glu-AMC, Z-LLE-AMC (5S,8S,11S)-5,8-Diisobutyl-11-((4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatetradecan-14-oic acid Z-LEU-LEU-GLY-AMC benzyloxycarbonyl-L-leucyl-L-leucyl-L-glutamic acid α-(4-methylcoumaryl-7-amide) Proteasome Substrate II L-α-Glutamine, N-[(phenylmethoxy)carbonyl]-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- 348086-66-8 C35H44N4O9 Proteasome substrate II.