3'-Deoxycytidine
![3'-Deoxycytidine Structure](CAS/GIF/7057-33-2.gif)
- CAS No.
- 7057-33-2
- Chemical Name:
- 3'-Deoxycytidine
- Synonyms
- 3-DC;antiviral agent;3'-DEOXYCYTIDINE;3’-deoxy-cytidin;3'-Deaxycytidine;3'-DEOXYCYTIDINE;3'-Deoxy-D-cytidine;Cytidine, 3'-deoxy-;3'-deoxyribicytidine;Pafolacianine Impurity 1
- CBNumber:
- CB6371476
- Molecular Formula:
- C9H13N3O4
- Molecular Weight:
- 227.22
- MOL File:
- 7057-33-2.mol
- Modify Date:
- 2024/7/2 8:55:14
Melting point | 230-232 °C |
---|---|
Boiling point | 497.6±55.0 °C(Predicted) |
Density | 1.73±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
pka | 14.01±0.60(Predicted) |
form | Solid |
color | White to light yellow |
InChI | InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-6(14)3-5(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1 |
InChIKey | ZHHOTKZTEUZTHX-SHYZEUOFSA-N |
SMILES | OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)C1 |
3'-Deoxycytidine Chemical Properties,Uses,Production
Uses
3'-Deoxycytidine is an inhibitor of nucleolar RNA synthesis but does not affect the appearance of mRNA. Displayed inhibitory properties against the replication of hepatitis C virus-like RNA template.
Biological Activity
3'-Deoxycytidine is a pyrimidine analog of cordycepin. The structures of cordycepin and 3'-deoxycytidine resemble adenosine and cytidine except for the altered 3' position in the ribose moiety, where hydrogen is substituted for the hydroxyl group. 3'-deoxycytidine affects similar to that of cordycepin on nucleolar RNA formation and has approximately the same level of activity as the adenosine analog. 3'-deoxycytidine, like cordycepin, enters cells and is phosphorylated by the appropriate enzymes. 3'-Deoxycytidine shares with cordycepin the ability to inhibit nucleolar RNA synthesis, but it does not affect the appearance of mRNA. Neither compound affects heterogeneous nuclear RNA (HnRNA)[1].
References
[1] Herbert T. Abelson, Sheldon Penman. “Messenger RNA formation: Resistance to inhibition by 3′-deoxycytidine.” Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis 277 1 (1972): Pages 129-133.
3'-Deoxycytidine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Gagri Global IT Services Pvt. Ltd. | +91-40-27170174, | Telangana, India | 1321 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
PANNACEAN(HENAN)MEDICINE SCIENCE TECHNOLOGIES LTD | 0371-55159968 18137130222 | China | 504 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10311 | 58 | Inquiry |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7621 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
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