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Oxiconazole

Oxiconazole Structure
CAS No.
64211-45-6
Chemical Name:
Oxiconazole
Synonyms
OXICONAZOLE;Oxiconazolum;OXICONAZOLC NITRATE;Oxiconazole Nitarte;1-(2,4-dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-(1-imidazolyl)ethanimine;1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)-ethanone O-(2,4-dichlorobenzyl) oxime;1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-yl-ethanimine;Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-
CBNumber:
CB6394620
Molecular Formula:
C18H13Cl4N3O
Molecular Weight:
429.13
MOL File:
64211-45-6.mol
MSDS File:
SDS
Modify Date:
2022/12/21 16:56:50

Oxiconazole Properties

Boiling point 576.8±60.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 6.14±0.12(Predicted)
CAS DataBase Reference 64211-45-6(CAS DataBase Reference)

Oxiconazole Chemical Properties,Uses,Production

Uses

Antifungal.
Oxiconazole (Oxistat) is a synthetic imidazole that works, in part, by inhibiting ergosterol 2,3-epoxidase synthesis and thereby disrupting cell membrane integrity.

Definition

ChEBI: An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and i which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.

Indications

Topical treatment of mycoses of the skin induced or sustained by fungi such as dermatophytes and yeasts. In addition, oxiconazole is indicated for therapy of vulvovaginal mycoses caused by Candida species and Candida (Torulopsis) glabrata.

Antimicrobial activity

Broad-specktrum imidazole antimycotic with activity against almost all species of pathogenic fungi.

Side effects

Local irritations such as itching and burning sensations, and allergic reactions may occur in rare cases and are mainly due to the galenic formulation.

Oxiconazole Preparation Products And Raw materials

Raw materials

Preparation Products

Oxiconazole Suppliers

Global( 63)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Wuhan Shengtianyi Bio-technology Co, Ltd. 027-81659576 13871306383 China 17 50 Inquiry

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  • Mar 30,2022
OXICONAZOLC NITRATE OXICONAZOLE 1-(2,4-Dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-imidazol-1-yl-ethanimine 1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)-ethanone O-(2,4-dichlorobenzyl) oxime 1-(2,4-dichlorophenyl)-N-[(2,4-dichlorophenyl)methoxy]-2-(1-imidazolyl)ethanimine Oxiconazole Nitarte Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)- Oxiconazolum 64211-45-6 C18H13N3OCl4HNO3 C18H13Cl4N3O Active Pharmaceutical Ingredients