ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Apoptosis >Caspase inhibitors >Z-DEVD-FMK

Z-DEVD-FMK

Z-DEVD-FMK Structure
CAS No.
210344-95-9
Chemical Name:
Z-DEVD-FMK
Synonyms
S7312;CS-1505;CTK8E8674;abs812077;Z-DEVD-FMK;AG-B-56189;CASPASE-3, INHIBITOR;CASPASE-3 INHIBITOR2;Z-DEVD-FMK USP/EP/BP;CASPASE-3 INHIBITOR II
CBNumber:
CB6453635
Molecular Formula:
C30H41FN4O12
Molecular Weight:
668.66
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

Z-DEVD-FMK Properties

Boiling point 914.2±65.0 °C(Predicted)
Density 1.260±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO/DMF: ≥20 mM
pka 10.26±0.46(Predicted)
form White to slightly brown solid
color White to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

Z-DEVD-FMK price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 264155 Caspase-3 Inhibitor II - CAS 210344-95-9 - Calbiochem The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is pri 210344-95-9 250μG ₹16250.01 2022-06-14 Buy
Sigma-Aldrich(India) 264155 Caspase-3 Inhibitor II - CAS 210344-95-9 - Calbiochem The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is pri 210344-95-9 1MG ₹46050 2022-06-14 Buy
Product number Packaging Price Buy
264155 250μG ₹16250.01 Buy
264155 1MG ₹46050 Buy

Z-DEVD-FMK Chemical Properties,Uses,Production

Uses

Z-DEVD-FMK is an irrversible caspase-3 inhibitor used as an anaesthetic agent. In addition, it is proposed to increase the longevity of platelet storage.

General Description

A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 μg/75 μl) solution of Z-DEVD-FMK (Cat. No. 264156) in DMSO is also available.

Biological Activity

Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo .

Z-DEVD-FMK Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 147)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32836 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24099 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Zhejiang Hangyu API Co., Ltd +8617531972939 China 2944 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Z-ASP-GLU-VAL-ASP-FLUOROMETHYLKETONE Z-ASP(OME)-GLU(OME)-VAL-ASP(OME)-CH2F Z-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE Z-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FMK Z-ASP(OME)-GLU(OME)-VAL-DL-ASP(OME)-FLUOROMETHYLKETONE Z-DEVD-FLUOROMETHYLKETONE Z-DEVD-FMK Z-D(OME)E(OME)VD(OME) FLUOROMETHYLKETONE Z-D(OME)E(OME)VD(OME)-FMK BENZYLOXYCARBONYL-ASP(OME)-GLU(OME)-VAL-ASP(OME)-FLUOROMETHYLKETONE CASPASE3/CPP32 INHIBITOR W-3 CASPASE-3, INHIBITOR CASPASE-3 INHIBITOR2 CASPASE-3 INHIBITOR (FLUOROMETHYLKETONE) CASPASE-3 INHIBITOR II L-Valinamide, N-[(phenylmethoxy)carbonyl]-L-α-aspartyl-L-α-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, 1,2-dimethyl ester N-[(Phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-valinamide 1,2-dimethyl ester Caspase-3 Inhibitor II - CAS 210344-95-9 - Calbiochem AG-B-56189 CASPASE-3 INHIBITOR II; 210344-95-9; CASPASE-3 INHIBITOR; CTK8E8674; AG-B-56189; S7312;CASPASE-3 INHIBITOR;210344-95-9 CTK8E8674 S7312 CS-1505 Caspase-2 Inhibitor Z-VDVAD-FMK Z-DEVD-FMK USP/EP/BP abs812077 Z-DEVD-FMK, Caspase-3 inhibitor CBZ-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OM) 210344-95-9 210334-95-9 C30H41N4O12F Inhibitors Apoptosis peptides API Caspases/Apoptosis peptide Caspase/Related Products Pepetides