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Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Z-PHE-DL-ALA-FLUOROMETHYLKETONE Structure
CAS No.
197855-65-5
Chemical Name:
Z-PHE-DL-ALA-FLUOROMETHYLKETONE
Synonyms
CS-1504;Z-Phe-DL-Ala-FMK;Z-PHE-DL-ALA-FLUOROMETHYLKETONE;Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide;Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate;Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk;Carbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester;SARS coronavirus,SARS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathepsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus replication,ZFAFMK
CBNumber:
CB9710726
Molecular Formula:
C21H23FN2O4
Molecular Weight:
386.42
MOL File:
197855-65-5.mol
Modify Date:
2024/7/2 8:55:42

Z-PHE-DL-ALA-FLUOROMETHYLKETONE Properties

Boiling point 630.5±55.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMF: 5 mg/ml; DMSO: 5 mg/ml
pka 11.07±0.46(Predicted)
form White solid
color White to off-white

SAFETY

Risk and Safety Statements

HS Code  29145090

Z-PHE-DL-ALA-FLUOROMETHYLKETONE Chemical Properties,Uses,Production

Description

Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain. It also inhibits effector caspases-2, -3, -6, and -7 (IC50 = 6-32 μM) without affecting the initiator caspases-8 and -10. Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses. It can be used both in cells and in vivo.

Uses

Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibits papain and cruzain.

Z-PHE-DL-ALA-FLUOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 84)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Z-PHE-DL-ALA-FLUOROMETHYLKETONE Carbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide CS-1504 Z-Phe-DL-Ala-FMK Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate SARS coronavirus,SARS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathepsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus replication,ZFAFMK 197855-65-5 C21H23FN2O4 Inhibitors API