DSIP

- CAS No.
- 62568-57-4
- Chemical Name:
- DSIP
- Synonyms
- DSIP;WAGGDASGE;DSIP 4H2O;EMIDELTIDE;Delta-Sleep;DSIP acetate;Etipolypeptide;DSIP USP/EP/BP;Ftpp/Adipotide;DSIP nonapeptide
- CBNumber:
- CB6478191
- Molecular Formula:
- C35H48N10O15
- Molecular Weight:
- 848.82
- MOL File:
- 62568-57-4.mol
- Modify Date:
- 2025/4/17 18:45:41
Boiling point | 1522.7±65.0 °C(Predicted) |
---|---|
Density | 1.458±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
form | Powder |
pka | 3.18±0.10(Predicted) |
color | White to off-white |
Water Solubility | Soluble in water at 0.5mg/ml |
Sequence | H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH |
InChIKey | ZRZROXNBKJAOKB-GFVHOAGBSA-N |
DSIP price More Price(2)
DSIP Chemical Properties,Uses,Production
Description
Delta-sleep-inducing peptide (DSIP) is a neuropeptide with amino acid sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and molecular mass 848.81 g/mol. DSIP occurs in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). Delta-sleep-inducing peptide is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.
Uses
Delta-sleep-inducing peptide (DSIP) was isolated, characterized, and synthesized more than 6 years ago. It can help relieve stress and aches that keep you from restful sleep. It was first proposed as a sleep-peptide and this remains the prevalent impression of its function. DSIP is a natural sleep-promoting nonapeptide with a few beneficial functions. The peptide has been used to treat poor sleep, pain conditions, stress-related symptoms, and more. Delta-Sleep Inducing Peptide trifluoroacetate salt H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH trifluoroacetate salt is a useful research chemical compound.
Uses
DSIP is thought to increase sleep regulation, reduce motor activity to improve deep sleep, stimulate ACTH and LH levels, and reportedly normalize blood pressure. DSIP can change the serum level of some hormones, such as adrenocorticotropic hormone, somatostatin, serotonin, etc.
Definition
Emideltide or DSIP is a nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal.
benefits
Can restore disturbed sleep patterns;Can promote LH and GH release;Can reduce persistent/chronic pain;Can modulate cortisol production.
benefits
Delta sleep-inducing peptide (DSIP), which suppresses excess production of free radicals in the CNS and prevents neuron death during the body’s response to stress. DSIP activates oxidative phosphorylation and increases the resistance of brain neurons to hypoxia in vitro. It decreases the sensitivity of neuron receptors to the excitatory actions of glutamate. Thus, DSIP helps to prevent excitotoxicity, which may underlie its neuroprotective action in cerebral ischemia[1].
References
[1] E. Koplik. “Delta sleep-inducing peptide and Deltaran: Potential approaches to antistress protection.” Neuroscience and Behavioral Physiology 38 1 (2008): 953–957.
DSIP Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Huaian Banting Trading Co., Ltd. | +8618875735705 | China | 57 | 58 | Inquiry |
Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 995 | 58 | Inquiry |
Anko Intermational Trade Limited | +86-18073326374 +86-18073326374 | China | 58 | 58 | Inquiry |
Apextide Co Ltd | +86-15300650552 +86-15300650552 | China | 92 | 58 | Inquiry |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3512 | 58 | Inquiry |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | China | 2555 | 58 | Inquiry |
Xi an Biohorlden Industry Trade Co Ltd | +86-18829283179 +86-13636819721 | China | 236 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | China | 8808 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3883 | 58 | Inquiry |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12809 | 58 | Inquiry |
Related Qustion
- Q:Is DSIP Delta-Sleep-Inducing Peptide Safety?
- A:However, like any peptide, DSIP has a few potential side effects. These may include headaches, dizziness, and gastrointestinal....
- May 15,2024
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