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OSELTAMIVIR ACID

OSELTAMIVIR ACID Structure
CAS No.
187227-45-8
Chemical Name:
OSELTAMIVIR ACID
Synonyms
Oseltamivir carboxylate;Oseltamivir impurity C;(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid;Gs4071;Gs 4071;Gs-4071;Aids095377;Aids-095377;Oseltamiviracid/GS4071;Oseltamivir acid, >=98%
CBNumber:
CB6501589
Molecular Formula:
C14H24N2O4
Molecular Weight:
284.35
MOL File:
187227-45-8.mol
Modify Date:
2024/7/2 8:55:14

OSELTAMIVIR ACID Properties

Melting point 183-185°C
Boiling point 508.7±50.0 °C(Predicted)
Density 1.15±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility ≥14.2 mg/mL in DMSO; ≥46.1 mg/mL in H2O with gentle warming; ≥97 mg/mL in EtOH with gentle warming
form Solid
pka 4.13±0.60(Predicted)
color White to off-white
EPA Substance Registry System 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- (187227-45-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  9999999999

OSELTAMIVIR ACID Chemical Properties,Uses,Production

Description

Oseltamivir (GS-4104) is an antiviral prodrug targeted against the influenza viruses. Oseltamivir acid is the active metabolite of oseltamivir. It acts as an inhibitor of influenza neuraminidases A and B (IC50 = 0.1 to 4.9 nM for both enzymes), in this way preventing virus budding and release.

Chemical Properties

White Solid

Uses

Oseltamivir Acid is a metabolite of Oseltamivir (O701000).

Definition

ChEBI: A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid which is substituted at positions 3, 4, and 5 by pentan-3-yloxy, acetamido, and amino groups, respectively (the 3R,4R,5S enantiomer). A antiviral drug, it is used as the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza.

OSELTAMIVIR ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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OSELTAMIVIR ACID Spectrum

Oseltamivir acid, >=98% Oseltamivir EP Impurity C Oseltamivir carboxylate (OC),Metabolite of oseltamivir (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohex-ene-1-carboxylic acid 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)- 204255-11-8 (Monophospate salt) Aids095377 Aids-095377 Gs 4071 Gs4071 Gs-4071 OseltamivirCarboxylicAcid,4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylicAcid OseltaMivir carboxylic acid (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylic acid Oseltamivir carboxylate (OC) Oseltamivir carboxylate (GS 4071 Oseltamivir Impurity476 Oseltamivir carboxylic acidQ: What is Oseltamivir carboxylic acid Q: What is the CAS Number of Oseltamivir carboxylic acid Q: What is the storage condition of Oseltamivir carboxylic acid Oseltamivir impurity C (Y0001340)Q: What is Oseltamivir impurity C (Y0001340) Q: What is the CAS Number of Oseltamivir impurity C (Y0001340) Oseltamivir Phosphate impurity C (EP) Oseltamivir Impurity 3 Monomer(Oseltamivir EP Impurity C Monomer) Oseltamivir acid formate salt Oseltamivir EP Impurity C (Oseltamivir Acid) (3R,4R,5S)-4-acetamido-5-amino-3 Oseltamivir Phosphate Impurity Ⅲ (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexence-1-carboxylic Acid Oseltamivir Impurity C (EP) Oseltamivir Carboxylic Acid HCl GS 4071;RO 64-0802;OSELTAMIVIR CARBOXYLATE Oseltamivir carboxylate Oseltamivir impurity C (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid Drug Metabolite,Inhibitor,Influenza Virus,Oseltamivir acid,GS4071,GS-4071,inhibit Oseltamiviracid/GS4071 Oseltamivir Phosphate Impurity C Oseltamivir Acid Impurity 187227-45-8 Various Metabolites and Impurities Metabolites Amines Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals