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RS 102895

RS 102895 Structure
CAS No.
300815-41-2
Chemical Name:
RS 102895
Synonyms
1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one;RS 102895 HYDROCHLORIDE;CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895;1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-;1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride;1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE
CBNumber:
CB6504368
Molecular Formula:
C21H21F3N2O2
Molecular Weight:
390.4
MOL File:
300815-41-2.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:10
Request For Quotation

RS 102895 Properties

Boiling point 446.1±45.0 °C(Predicted)
Density 1.33±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. Desiccate at RT
solubility DMSO: 18 mg/mL, clear, colorless
form powder
pka 13.46±0.20(Predicted)
color white

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

RS 102895 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) R1903 RS 102895 hydrochloride ≥98% (HPLC), powder 300815-41-2 5MG ₹23576.85 2022-06-14 Buy
Product number Packaging Price Buy
R1903 5MG ₹23576.85 Buy

RS 102895 Chemical Properties,Uses,Production

Uses

RS 102895 is a CCR2-selective chemokine receptor inhibitor.

Biological Activity

CCR2-selective chemokine receptor antagonist (IC 50 values are 0.36 and 17.8 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC 50 values of 32 nM and 1.7 μ M respectively. Also inhibits α 1A , α 1D and 5-HT 1A receptors.

RS 102895 Preparation Products And Raw materials

Raw materials

Preparation Products

RS 102895 Suppliers

Global( 95)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shanghai UCHEM Inc. +862156762820 +86-13564624040 China 7034 58 Inquiry
Henan Aochuang Chemical Co.,Ltd. +86-0371-63689365 +8618638391208 China 9425 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Hefei Xiuhe Biotechnology Co. Ltd. 0551-62887095 13856031416 China 172 58 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 China 12308 58 Inquiry
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 China 27314 60 Inquiry
Supplier Advantage
Shanghai UCHEM Inc. 58
Henan Aochuang Chemical Co.,Ltd. 58
LEAPCHEM CO., LTD. 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Hefei Xiuhe Biotechnology Co. Ltd. 58
Riedel-de Haen AG 87
Beijing Jin Ming Biotechnology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60

300815-41-2(RS 102895)Related Search:

2,3-Dichloro-5-(trifluoromethyl)pyridine 2-fluoro-6-(trifluoroMethyl)benzene-1-sulfonyl chloride Inter-trifluoromethyl iodobenzene 4-(2-AMINOPHENYL)-1-PHENETHYLPIPERIDINE 4-(O-AMINO-PHENYL) PIPERIDINE HYDROCHLORIDE
RS 102895 1-Phenethyl-4-phenyl-4-piperidinol SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE
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1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride RS 102895 HYDROCHLORIDE 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one 1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]- 1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895 1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride 300815-41-2 C21H21F3N2O2HCl RS 102895 CCR2-selective chemokine receptor antagonist. Cytokine signaling