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RS 102895

RS 102895 Structure
  • ₹23576.85
  • Product name: RS 102895
  • CAS: 300815-41-2
  • MF: C21H21F3N2O2
  • MW: 390.4
  • EINECS:
  • MDL Number:MFCD05865241
  • Synonyms:1'-(4-(TrifluoroMethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;RS 102895 HYDROCHLORIDE;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4h-3,1-benzoxazine-4,4'-peperidin]-2(1h)-one;1'-[2-[4-(TRIFLUOROMETHYL)PHENYL]ETHYL]-SPIRO[4H-3,1-BENZOXAZINE-4,4'-PIPERIDIN]-2(1H)-ONE HYDROCHLORIDE;1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one,hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-;1'-(4-(trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one;CC chemokine receptor,CCR,Inhibitor,RS102895,inhibit,RS-102895,RS 102895
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberR1903
  • Product descriptionRS 102895 hydrochloride ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹23576.85
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) R1903 RS 102895 hydrochloride ≥98% (HPLC), powder 5MG ₹23576.85 2022-06-14 Buy

Properties

Boiling point :446.1±45.0 °C(Predicted)
Density :1.33±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :Desiccate at RT
solubility :DMSO: 18 mg/mL, clear, colorless
form :powder
pka :13.46±0.20(Predicted)
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

RS 102895 Hydrochloride is a CKR-2B (CCR2)-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CKR-2B and CKR-1 (CCR2b and CCR1 receptors) respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Inhibits α1A-AR, α1D-AR and SR-1A (α1A, α1D and 5-HT1A receptors).

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Suppliers and manufacturers

Henan Aochuang Chemical Co.,Ltd.
RS 102895
₹0.00 /1kg
RS 102895 CAS:300815-41-2
Shanghai UCHEM Inc.
LEAPCHEM CO., LTD.
Jilin Chinese Academy of Sciences-yanshen Technology
Aladdin Scientific
Amadis Chemical Company Limited Hefei Xiuhe Biotechnology Co. Ltd. Riedel-de Haen AG Beijing Jin Ming Biotechnology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd.