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Methoxycarbonyl-L-tert-leucine

Methoxycarbonyl-L-tert-leucine Structure
CAS No.
162537-11-3
Chemical Name:
Methoxycarbonyl-L-tert-leucine
Synonyms
(S)-2-acetamido-3,3-dimethylbutanoic acid;MOC-L-tert.Leucine;N-Methoxycarbonyl-tert-leucine;(S)-2-(MethoxycarbonylaMino)-3,3-diMethylbutanoic acid;Moc-L-tle;Moc-Tle-OH;MOC-L-Norleucine;Moc-L-tert-lecine;MOC-L-tert. Leucin;Atazanavir USP RC A
CBNumber:
CB6663762
Molecular Formula:
C8H15NO4
Molecular Weight:
189.21
MOL File:
162537-11-3.mol
Modify Date:
2024/7/2 8:55:14

Methoxycarbonyl-L-tert-leucine Properties

Melting point 1090C
Boiling point 320.9±25.0 °C(Predicted)
Density 1.126±0.06 g/cm3(Predicted)
vapor pressure 0Pa at 25℃
storage temp. 2-8°C
solubility Soluble in ethyl acetate and methanol.
pka 4.46±0.10(Predicted)
form powder
color White to off-white
Water Solubility 26.4g/L at 20℃
InChI InChI=1S/C8H15NO4/c1-8(2,3)5(6(10)11)9-7(12)13-4/h5H,1-4H3,(H,9,12)(H,10,11)/t5-/m1/s1
InChIKey NWPRXAIYBULIEI-RXMQYKEDSA-N
SMILES C(O)(=O)[C@H](C(C)(C)C)NC(OC)=O
LogP 0.832 at 21℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2933399090
NFPA 704
1
1 0

Methoxycarbonyl-L-tert-leucine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR3001 Atazanavir Related Compound A pharmaceutical secondary standard, certified reference material 162537-11-3 50MG ₹41308.2 2022-06-14 Buy
ALFA India ALF-H35148-14 N-Methoxycarbonyl-L-tert-leucine, 98% 162537-11-3 25g ₹62501 2022-05-26 Buy
ALFA India ALF-H35148-06 N-Methoxycarbonyl-L-tert-leucine, 98% 162537-11-3 5g ₹7074 2022-05-26 Buy
ALFA India ALF-H35148-03 N-Methoxycarbonyl-L-tert-leucine, 98% 162537-11-3 1g ₹3114 2022-05-26 Buy
Product number Packaging Price Buy
PHR3001 50MG ₹41308.2 Buy
ALF-H35148-14 25g ₹62501 Buy
ALF-H35148-06 5g ₹7074 Buy
ALF-H35148-03 1g ₹3114 Buy

Methoxycarbonyl-L-tert-leucine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

The coupling of the two key intermediates, N-(methoxycarbonyl)-l-tert-leucine acylated benzyl hydrazine and chloromethyl ketone, via an S N 2 reaction furnished the amino ketone in high yield under our optimized conditions in practical synthesis of the HIV Protease Inhibitor Atazanavir via a Highly diastereoselective Reduction Approach.

Methoxycarbonyl-L-tert-leucine Preparation Products And Raw materials

Global( 448)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SURVIVAL TECHNOLOGIES LIMITED +91 8108285261 Gujarat, India 294 58 Inquiry
OPULENT PHARMA +91-9106692785 +91-9106692785 Gujarat, India 479 58 Inquiry
Chemicea Pharmaceuticals Pvt Ltd +91-918482849343 +91-8482849343 Mumbai, India 461 58 Inquiry
AMINO ORGANICS +919866989891 Hyderabad, India 275 58 Inquiry
SV CHEM INTERMEDITES PRIVATE LIMITED +91-9940629423 +91-9940629423 Tamil Nadu, India 202 58 Inquiry
Atul Bioscience Ltd +91-9316723499 +91-9316723499 Maharashtra, India 43 58 Inquiry
Arch Pharmalabs Ltd +91-2242871210 +91-2242871210 Maharashtra, India 51 58 Inquiry
Optimus Pharma Pvt Ltd (Sekhmet Pharmaventures)) +91-9100091731 +91-9573334999 Telangana, India 57 58 Inquiry
OMSAV Pharma Research Pvt Ltd +91-9987998884 +91-9987759453 NaviMumbai, India 11 58 Inquiry
Medec Dragon Private Limited +91-9768474716 Maharashtra, India 59 58 Inquiry
(S)-2-Methoxycarbonylamino-3,3-dimethylbutyric acid Methoxycarbonyl-L-tert-leucine N-(Methoxycarbonyl)-3-methyl-L-valine Atazanavir related coMpound A MOC-L-tert. Leucin L-Valine,N-(Methoxycarbonyl)-3-Methyl- Moc-L-tert-lecine (S)-2-(Methoxycarbonyl)-3,3-diMethylbutanoic acid Methyl Carbonyl L-tert Leucine (2S)-2-ACETAMIDO-3,3-DIMETHYLBUTANOIC ACID N-Moc-L-tert-Leucine (S)-N-(METHOXYCARBONYL)-TERT-LEUCINE Methylcarbonyl-L-t-Leucine Atazanavir USP Related Compound A Methoxycarbonyl-L-tert-leucinef Atazanavir side chain Atazanavir Impurity 15 Atazanavir USP RC A N-Methoxycarbonyl-L-tert-leucine,98% Methoxycarbonyl-L-tert-leucine USP/EP/BP Moc-Tle-OH Atazanavir Related Compund A (Methoxycarbonyl-L-tert-leucine) Atazanavir Related Compound A ((S)-2-[(Methoxycarbonyl)amino]-3,3-dimethylbutanoic acid) (1044356) MOC-L-tert.Leucine N-Methoxycarbonyl-tert-leucine (S)-2-(MethoxycarbonylaMino)-3,3-diMethylbutanoic acid (S)-2-acetamido-3,3-dimethylbutanoic acid Atazanavir Sulfate Impurity K MOC-L-Norleucine Atazanavir Sulfate EP Impurity K Moc-L-tle N-(Methoxycarbonyl)-tert-L-leucine 162537-11-3 C38H54N6O11S Amino Acid Derivatives Amino Acids 13C, 2H, 15N Amino Acids & Derivatives Chiral Reagents