ALMITRINE
- CAS No.
- 27469-53-0
- Chemical Name:
- ALMITRINE
- Synonyms
- S-2620;ALMITRINE;AlMitrine Mesylate;ALMITRINE USP/EP/BP;Almitrine dimethanesulfonic acid;2,4-Bis(allylamino)-6-[4-[bis(p-fluorophenyl)methyl]-1-piperazinyl]-s-triazine;1-[2,4-Bis(allylamino)-1,3,5-triazin-6-yl]-4-[bis(4-fluorophenyl)methyl]piperazine;6-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]-N,N'-di(2-propenyl)-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, 6-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-N2,N4-di-2-propen-1-yl-
- CBNumber:
- CB6667472
- Molecular Formula:
- C26H29F2N7
- Molecular Weight:
- 477.55
- MOL File:
- 27469-53-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/4/23 13:52:06
ALMITRINE Chemical Properties,Uses,Production
Uses
Respiratory stimulant.
Definition
ChEBI: A triamino-1,3,5-triazine compound having allylamino substituents at the 2- and 4-positions and a 4-(bis(p-fluorophenyl)methyl)-1-piperazinyl group at the 6-position.
World Health Organization (WHO)
Peripheral neuropathy has been reported in a few patients receiving almitrine for long periods. The indications for treatment have consequently been restricted in the Federal Republic of Germany. Some other countries have advised doctors to maintain patients under close supervision throughout treatment and to restrict dosage to two out of every three months.
Pharmacology
Almitrine, like doxapram, increases the rate and depth of respiration. In addition, it is believed that it redistributes pulmonary blood circulation, increasing it in alveoli, which leads to relatively better pulmonary ventilation. It has a more prolonged effect than doxapram.
Safety Profile
Poison by intraperitoneal andintravenous routes. When heated to decomposition itemits very toxic fumes of F?? and NOx.
ALMITRINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
| SIMAGCHEM CORP | +86-13806087780 | China | 17365 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22854 | 58 | Inquiry |
| Xiamen Eagle Chemical Limited Corporation | China | 5688 | 58 | Inquiry | |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-58851090 17714375163 | China | 13012 | 58 | Inquiry |
| Absin Bioscience Inc. | 021-38015121-8802 | CHINA | 6208 | 58 | Inquiry |
| Shanghai Yaji Biotechnology Co., Ltd. | 021-34661275 | CHINA | 6857 | 58 | Inquiry |
| Shanghai Guangrui Biological Technology Co., Ltd. | 021-35323056 | CHINA | 4273 | 58 | Inquiry |
| SINO High Goal Chemical Technology Co., Ltd. | 021-57646680 18306277365 | China | 2583 | 58 | Inquiry |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | China | 4398 | 58 | Inquiry |
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