Chinese english Japanese Germany Korea

Cefcapene

Cefcapene Structure
CAS No.
135889-00-8
Chemical Name:
Cefcapene
Synonyms
CEFCAPENE;s1006;Cefcamate;Cefcarpinic Acid;CEFCAPENE Impurity;Cefcapene Impurity 5;Cefcapene Impurity 7;Cefcapene pivoxil free acid;Cefcapene Pivoxil Impurity 1;Cefcapene pivoxil Impurity 16
CBNumber:
CB6680909
Molecular Formula:
C17H19N5O6S2
Molecular Weight:
453.49
MOL File:
135889-00-8.mol
MSDS File:
SDS
Modify Date:
2024/4/25 17:59:01
Request For Quotation

Cefcapene Properties

Boiling point 936.0±65.0 °C(Predicted)
Density 1.63
pka 2.58±0.50(Predicted)

Cefcapene Chemical Properties,Uses,Production

Uses

Cefcapene is a metabolite of Cefcapene Pivoxil (C242550). Antibacterial, orally absorbed cephalosporin that is used in the treatment of bacterial infections.

Definition

ChEBI: Cefcapene is a cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. It has a role as an antibacterial drug. It is a cephalosporin, a carboxylic acid, a carbamate ester, an enamide, a member of 1,3-thiazoles and a secondary carboxamide.

Antimicrobial activity

A semisynthetic cephalosporin formulated for oral administration as the prodrug ester, cefcapene pivoxil. Activity and uses are similar to those of cefditoren.
Available in Japan.

Pharmacokinetics

Cefcapene is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcapene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
6436055

Cefcapene Preparation Products And Raw materials

Raw materials

Preparation Products

Cefcapene Suppliers

Global( 78)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Xiamen AmoyChem Co., Ltd +86-592-6051114 +8618959220845 China 6387 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Supplier Advantage
OCEAN TRADING CORPORATION 58
career henan chemical co 58
Xiamen AmoyChem Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
SIMAGCHEM CORP 58
BOC Sciences 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
GIHI CHEMICALS CO.,LIMITED 58
China National Standard Pharmaceutical Corporation Limited 58

135889-00-8(Cefcapene)Related Search:

(Z)-2-(2-tert-Butoxycarbonylaminothiazol-4-yl)-2-pentenoic acid Precursor of cefcapene diisopropylanmine salt Cefetamet hydrochloride cefcapene pivoxil hydrochloride CEFCAPENE PIVOXIL HCL
CEFCAPENE PIVOXIL-D9 Cefcapene Pivoxil Hydrochlrode JP CEFCAPENE PIVOXIL Cefcapene Hydroxymethyl-7-Aminocephalosporanic acid
7-AMCA
chevron_left

1of3

chevron_right
s1006 (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-pentenoylamino]-8-oxo-3-(carbamoyloxymethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (7R)-7-[[(Z)-2-(2-Amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-3-[(carbamoyloxy)methyl]cepham-3-ene-4-carboxylic acid Cefcamate Cefcapene pivoxil free acid 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,3-[[(aMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-,(6R,7R)- (6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-aMino-4-thiazolyl)-1-oxo-2-penten-1-yl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicaci Cefcarpinic Acid (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Cefcapene Impurity 5 Cefcapene Pivoxil Impurity 1 Cefcapene Pivoxil Impurity 4 (Cefcapene) Cefcapene Impurity 7 CEFCAPENE Cefcapene pivoxil Impurity 16 CEFCAPENE Impurity Cefcapene Pivoxil Hydrolized Impurity 1 135889-00-8 C23H29N5O8S2 C17H19N5O6S2 Chiral Reagents Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Sulfur & Selenium Compounds