Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate

Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate Structure
CAS No.
74892-82-3
Chemical Name:
Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate
Synonyms
Ethyl (2R;Argatroban Impurity 49;Argatraban Intermediate -1;Ethyl (2R,4R)-4-Methylpipecolate;4R)-4-methyl-2-piperidinecarboxylate;(2R,4R)4-methylpiperidecarboxylicacid;(2R,4R)-4-METHYL-2-PIPERIDINECARBOXYLATE;ethyl (2R,4R)-4-Methylpiperidine-2-carboxylate;(2R,4R)-ETHYL 4-METHYLPIPERIDINE-2-CARBOXYLATE;ethyl (2r,4r)-4-methyl-2-piperidinecarboxylate
CBNumber:
CB6718064
Molecular Formula:
C9H17NO2
Molecular Weight:
171.24
MOL File:
74892-82-3.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:54

Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate Properties

Boiling point 226.1±33.0 °C(Predicted)
Density 0.969±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility Chloroform (Sparingly), Ethanol (Slightly), Methanol (Soluble)
form Oil
pka 6.65±0.10(Predicted)
color Light Yellow to Yellow
CAS DataBase Reference 74892-82-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P305+P351+P338
HS Code  29333990

Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate Chemical Properties,Uses,Production

Chemical Properties

light yellow solution

Uses

Ethyl (2R,4R)-4-Methylpipecolate is an intermediate in the preparation of Argatroban (A769000).

Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate Preparation Products And Raw materials

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(2R,4R)4-methylpiperidecarboxylicacid (2R,4R)-ETHYL 4-METHYLPIPERIDINE-2-CARBOXYLATE (2R,4R)-4-METHYL-2-PIPERIDINECARBOXYLATE (2R,4R)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester ethyl (2r,4r)-4-methyl-2-piperidinecarboxylate (2R-trans)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester Ethyl (2R,4R)-4-Methylpipecolate ethyl (2R,4R)-4-Methylpiperidine-2-carboxylate (2R,4R)-4-Methyl-2-piperidinecarboxylate, ee: 96% Argatraban Intermediate -1 (2R,4R)-4-Methyl-2-piperidinecarboxylate, 98%, ee: 96% Argatroban Impurity 49 2-Piperidinecarboxylic acid, 4-methyl-, ethyl ester, (2R,4R)- 4R)-4-methyl-2-piperidinecarboxylate Ethyl (2R 74892-82-3 Heterocycle-other series Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals