β-Elemonic Acid
- CAS No.
- 28282-25-9
- Chemical Name:
- β-Elemonic Acid
- Synonyms
- β-Elemonic;Beta-EleMonic;elemonic acid;β-deMonic acid;β-demonic-acid;B-ELEMONIC ACID;β-Elemonic acid;β-Elemonic acid;Elemadienonic acid;BETA-ELEMONIC ACID
- CBNumber:
- CB6737997
- Molecular Formula:
- C30H46O3
- Molecular Weight:
- 454.68
- MOL File:
- 28282-25-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:14
β-Elemonic Acid Chemical Properties,Uses,Production
Description
β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro.
Uses
β-Elemonic Acid inhibits cell proliferation of human lung adenocarcinoma A549 cells and role of MAPK, ROS activation and glutathione depletion. Elemonic acid is also a Pin1 inhibitors.
β-Elemonic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | China | 952 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3777 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 11506 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +8619930503259 | China | 18433 | 58 | Inquiry |