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Timosaponin A-III

Timosaponin A-III Structure
CAS No.
41059-79-4
Chemical Name:
Timosaponin A-III
Synonyms
Filiferin B;XilingsaponinA;TIMOSAPONIN A-;AnemarsaponinA3;TIMOSAPONIN A-3;Timosaponin A-III;Timosaponine A III;Timosaponin A-Ⅲ Standard;TIMOSAPONIN A3 (SYN. TIMOSAPONIN A-III);β-D-Galactopyranoside, (3β,5β,25S)-spirostan-3-yl2-O-β-D-glucopyranosyl-
CBNumber:
CB6777636
Molecular Formula:
C39H64O13
Molecular Weight:
740.92
MOL File:
41059-79-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

Timosaponin A-III Properties

Melting point 317-322 °C
Boiling point 862.8±65.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml
form White to off white solid.
pka 12.85±0.70(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
NFPA 704
0
2 0

Timosaponin A-III Chemical Properties,Uses,Production

Uses

Timosaponin A3 suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells.Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator.

Timosaponin A-III Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 182)Suppliers
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CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
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TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry

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Timosaponin A-III Spectrum

[(25S)-5β-Spirostan-3β-yl]2-O-(β-D-glucopyranosyl)-β-D-galactopyranoside Timosaponin A-III TIMOSAPONIN A3 (SYN. TIMOSAPONIN A-III) TIMOSAPONIN A-3 TIMOSAPONIN A- AnemarsaponinA3 Filiferin B XilingsaponinA β-D-Galactopyranoside, (3β,5β,25S)-spirostan-3-yl2-O-β-D-glucopyranosyl- Timosaponin A-Ⅲ Standard Timosaponine A III (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(((2aR,2'R,4S,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 41059-79-4 C39H64O13 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract The group of Anemarrhenae