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(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Structure
CAS No.
7101-51-1
Chemical Name:
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
Synonyms
DOPA-METHYLESTER;L-DOPA Methyl Ester;levodopa methyl ester;Methyl 3-hydroxy-L-tyrosinate;3-Hydroxy-L-Tyrosine methyl ester;L-Tyrosine, 3-hydroxy-, Methyl ester;(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate;methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate;(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER;(S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride
CBNumber:
CB6811125
Molecular Formula:
C10H13NO4
Molecular Weight:
211.21
MOL File:
7101-51-1.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:41
Request For Quotation

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Properties

Boiling point 350.89°C (rough estimate)
Density 1.2545 (rough estimate)
refractive index 1.5150 (estimate)
storage temp. 2-8°C
form solid
pka 9.67±0.20(Predicted)
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P304+P340
HS Code  2922500090

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Chemical Properties,Uses,Production

Description

CHF-1301 was launched as an injection in Italy for the treatment of patients with Parkinson's disease, particularly those with complications in their clinical responses. CHF-1301 is the methyl ester of L-Dopa (levodopa), the immediate precursor of dopamine. Thus, this prodrug is more soluble in water at physiological pH, better absorbed and slowly transformed into levodopa in vivo; it consequently improves the duration of action and prevents the rapid fluctuations in response or involontary movements (dyskinesia) observed during chronic treatment with levodopa. In patients with a delayed effect of levodopa (on-phenomenon) or a severe resistance to L-Dopa (off-phenomenon), CHF- 1301 significantly improves the onset and the stability of the'response.

Originator

Chiesi Farmaceutici SpA (Italy)

brand name

Levomet

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-Methyl 2-((tert-butoxycarbonyl)aMino)-3-(3,4-dihydroxyphenyl)propanoate

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER Suppliers

Global( 18)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aromsyn Co., Ltd. +86-0571-85585865 +8613336024896 China 19185 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
DONBOO AMINO ACID COMPANY +8613063595538 China 9365 58 Inquiry
ChemPacific Corporation 410 633 5771 United States 6902 51 Inquiry
APAC Pharmaceutical, LLC +1(410) 997 5552 United States 6332 38 Inquiry
AlliChem, LLC 301-317-5072 United States 6527 60 Inquiry
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216 China 9394 52 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
TargetMol Chemicals Inc. 58
Aromsyn Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
DONBOO AMINO ACID COMPANY 58
ChemPacific Corporation 51
APAC Pharmaceutical, LLC 38
AlliChem, LLC 60
Hangzhou Yuhao Chemical Technology Co., Ltd 52

7101-51-1((S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER)Related Search:

Ethyl methyldopate hydrochloride Benzyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate Levodopa L-3,4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE (S)-3,4-DIMETHOXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE
(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER METHYL (2S)-2-AMINO-3-(3-HYDROXY-4-METHOXYPHENYL)PROPANOATE (S)-3,4-DIMETHOXYPHENYLALANINE METHYL ESTER METHYL (2S)-2-AMINO-3-(3,4,5-TRIMETHOXYPHENYL)PROPANOATE (S)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINE CARBOXYLIC TERT BUTYL ESTER
METHYL (2S)-2-AMINO-3-[4-METHOXY-3-(PHENYLMETHOXY)PHENYL]PROPANOATE METHYL (2S)-2-AMINO-3-(5-BROMO-3,4-DIMETHOXYPHENYL)PROPANOATE METHYL 3-(2H-BENZO[3,4-D]1,3-DIOXOLEN-5-YL)(2S)-2-AMINOPROPANOATE 3-O-METHYL-4-O-BOC-6-TRIMETHYLSTANNYL-L-DOPA METHYLDOPA METHYL ESTER
METHYL (2S)-2-AMINO-3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANOATE L-TYROSINE, 5-[[(1,1-DIMETHYLETHOXY)CARBONYL]OXY]-N-[(1,1-DIMETHYLETHOXY)CARBONYL]-2-(TRIMETHYLSTANNYL)-, METHYL ESTER, 1,1-DIMETHYLETHYL CARBONATE N-BENZOYL-2-HYDROXY-4,5-DIMETHOXYPHENYLALANINE ETHYL ESTER
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(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER levodopa methyl ester DOPA-METHYLESTER L-DOPA Methyl Ester (S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride L-Tyrosine, 3-hydroxy-, Methyl ester Methyl 3-hydroxy-L-tyrosinate methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate 3-Hydroxy-L-Tyrosine methyl ester (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate MelevodopaQ: What is Melevodopa Q: What is the CAS Number of Melevodopa Q: What is the storage condition of Melevodopa 7101-51-1