Ethyl methyldopate hydrochloride
![Ethyl methyldopate hydrochloride Structure](CAS/GIF/2508-79-4.gif)
- CAS No.
- 2508-79-4
- Chemical Name:
- Ethyl methyldopate hydrochloride
- Synonyms
- METHYLDOPATE HCL;METHYLDOPAETHYLHCL;Ethyl ester hydrochloride;METHYLDOPATE HYDROCHLORIDE;QSRVZCCJDKYRRF-YDALLXLXSA-N;Aldomet Ester hydrochloride;methyldopa ethyl hydrochloride;Ethyl methyldopa hydrochloride;ethyl methyldopate hydrochloride;Methyldopate Hydrochloride (200 mg)
- CBNumber:
- CB3746806
- Molecular Formula:
- C12H18ClNO4
- Molecular Weight:
- 275.73
- MOL File:
- 2508-79-4.mol
- Modify Date:
- 2022/12/21 16:56:50
Ethyl methyldopate hydrochloride Chemical Properties,Uses,Production
Uses
Ethyl methyldopate hydrochloride is Antihypertensive.
General Description
Methyldopatehydrochloride, L-3-(3,4-dihydroxyphenyl)-2-methylalanineethyl ester hydrochloride (Aldomet ester hydrochloride), α-methyldopa, lowers blood pressure by inhibitingthe outflow of sympathetic vasoconstrictor impulses fromthe brain. Early studies had suggested that the hypotensiveaction of α-methyldopa was a result of the peripheral propertiesof the drug as a decarboxylase inhibitor or a falsetransmitter.
Clinical Use
Ethyl methyldopate hydrochloride is used as a step 2 agent and is recommendedfor patients with high blood pressure who are not responsiveto diuretic therapy alone. Ethyl methyldopate hydrochloride, suitable for oral use,is a zwitterion and is not soluble enough for parenteral use.The problem was solved by making the ester, leaving theamine free to form the water-soluble hydrochloride salt. It issupplied as a stable, buffered solution, protected with antioxidantsand chelating agents.
Ethyl methyldopate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
Hebei Guanlang Biotechnology Co., Ltd. | +8619930503259 | China | 18433 | 58 | Inquiry |
PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | China | 35426 | 58 | Inquiry |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | China | 9311 | 58 | Inquiry |
DONBOO AMINO ACID COMPANY | +8613063595538 | China | 9365 | 58 | Inquiry |