Ethyl cellulose
- CAS No.
- 9004-57-3
- Chemical Name:
- Ethyl cellulose
- Synonyms
- ets;ethocel;MODIFIED CELLULOSE;g50;t100;g200;spt50cps;nixone/c;aquacoat;ethocele7
- CBNumber:
- CB6165620
- Molecular Formula:
- C23H24N6O4
- Molecular Weight:
- 448.47446
- MOL File:
- 9004-57-3.mol
- Modify Date:
- 2024/5/23 18:06:45
| Melting point | 240-255 °C |
|---|---|
| Density | 1.14 g/mL at 25 °C (lit.) |
| refractive index |
n |
| storage temp. | 2-8°C |
| solubility | esters, aromatic hydrocarbons, alcohols and ketones: soluble |
| form | powder |
| color | White to slightly yellow |
| Specific Gravity | 1.14 |
| Water Solubility | insoluble |
| Merck | 14,3781 |
| Dielectric constant | 2.8（Ambient） |
| EPA Substance Registry System | Ethyl cellulose (9004-57-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H313-H319-H315-H303-H335-H412 | |||||||||
| Precautionary statements | P312-P312-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P273-P501 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | FJ5950500 | |||||||||
| F | 3 | |||||||||
| Autoignition Temperature | 698 °F | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 39129000 | |||||||||
| NFPA 704 |
|
Ethyl cellulose price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 46080 | Ethyl cellulose 48.0-49.5% (w/w) ethoxyl basis | 9004-57-3 | 250G | ₹10456.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46080 | Ethyl cellulose 48.0-49.5% (w/w) ethoxyl basis | 9004-57-3 | 250G | ₹10456.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46080 | Ethyl cellulose 48.0-49.5% (w/w) ethoxyl basis | 9004-57-3 | 1KG | ₹22667.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46070 | Ethyl cellulose 48.0-49.5% (w/w) ethoxyl basis | 9004-57-3 | 250G | ₹11788.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 46070 | Ethyl cellulose 48.0-49.5% (w/w) ethoxyl basis | 9004-57-3 | 1KG | ₹25503.7 | 2022-06-14 | Buy |
Ethyl cellulose Chemical Properties,Uses,Production
Chemical Properties
white to slightly yellowish powder
Chemical Properties
Ethyl celluloses are low density polymers (1070–1180 kg.m–3) with solubilities depending on the degree of ethylation; usually commercial grade contains 44–48% ethoxyl functional groups. Solid masses of ethylcellulose exhibit low absorption of moisture, excellent dimensional stability and low temperature toughness and impact resistance. Chemically they are less resistant towards acids than cellulose esters but much more resistant to alkalis. They can be processed by injection molding. Because ethylcellulose is soluble in a wide variety of solvents, it provides a wide variety of varnish formulations. Benzylcelluloses yield plastics with excellent dielectric properties and chemical stability.
Uses
ethyl cellulose is a binder, film former, and thickener. It is used in suntan gels, creams, and lotions. This is the ethyl ether of cellulose.
Preparation
Ethyl cellulose is prepared by reacting cellulose with caustic to form caustic cellulose, which is then reacted with chloroethane to form ethyl cellulose. Plasticgrade material contains 44-48% ethoxyl.
Although not as resistant as cellulose esters to acids, it is much more resistant to bases. An outstanding feature is its toughness at low temperatures.
Production Methods
Ethylcellulose is prepared by treating purified cellulose (sourced
from chemical-grade cotton linters and wood pulp) with an alkaline
solution, followed by ethylation of the alkali cellulose with
chloroethane as shown below, where R represents the cellulose
radical:
RONa + C2H5Cl→ROC2H5+NaCl
The manner in which the ethyl group is added to cellulose can be
described by the degree of substitution (DS). The DS designates the
average number of hydroxyl positions on the anhydroglucose unit
that have been reacted with ethyl chloride. Since each anhydroglucose
unit of the cellulose molecule has three hydroxyl groups, the
maximum value for DS is three.
Safety Profile
Low toxicity by ingestion and skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes
Safety
Ethylcellulose is widely used in oral and topical pharmaceutical
formulations. It is also used in food products. Ethylcellulose is not
metabolized following oral consumption and is therefore a
noncalorific substance. Because ethylcellulose is not metabolized it
is not recommended for parenteral products; parenteral use may be
harmful to the kidneys.
Ethylcellulose is generally regarded as a nontoxic, nonallergenic,
and nonirritating material.
As ethylcellulose is not considered to be a health hazard, the
WHO has not specified an acceptable daily intake. The highest
reported level used in an oral product is 308.8 mg in an oral
sustained release tablet.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg
storage
Ethylcellulose is a stable, slightly hygroscopic material. It is
chemically resistant to alkalis, both dilute and concentrated, and
to salt solutions, although it is more sensitive to acidic materials
than are cellulose esters.
Ethylcellulose is subject to oxidative degradation in the presence
of sunlight or UV light at elevated temperatures. This may be
prevented by the use of antioxidant and chemical additives that
absorb light in the 230–340nm range.
Ethylcellulose should be stored at a temperature not exceeding
32°C (90°F) in a dry area away from all sources of heat. It should
not be stored next to peroxides or other oxidizing agents.
Incompatibilities
Incompatible with paraffin wax and microcrystalline wax.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral capsules, suspensions and tablets; topical emulsions and vaginal preparations). Included in nonparenteral medicines licensed in Europe. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Ethyl cellulose Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 32 | 58 | Inquiry |
| Prachin Chemical | +91-7922821740 +91-9825015645 | Gujarat, India | 21 | 58 | Inquiry |
| S D Fine Chem Limited | +91-9323715856 +91-9323715856 | Maharashtra, India | 368 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Nakoda Corporation | 08048959416 | Madhya Pradesh, India | 16 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Otto Chemie Pvt. Ltd. | 58 |
| Prachin Chemical | 58 |
| S D Fine Chem Limited | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| Central Drug House(P) Ltd. | 58 |
| LOBA CHEMIE PVT.LTD. | 58 |
| Triveni chemicals | 58 |
| Nakoda Corporation | 58 |